Drug Stats Flashcards

1
Q

What drug has the highest % non-ionized?

A

Alfentanil

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2
Q

What drug has the Lowest % non-ionized?

A

Meperidine

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3
Q

What drug has the highest % protein binding?

A

Sufentanil

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4
Q

What drug has the lowest % protein binding?

A

Morphine

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5
Q

Highest clearance? mL/min

A

Remifantanil

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6
Q

Lowest clearance?

A

Alfentanil

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7
Q

Highest Vd?

A

Fentanyl

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8
Q

Lowest VD?

A

Alfentanil

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9
Q

Highest partition coefficeint?

A

sufentanil

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10
Q

Lowest partition coefficient

A

morphine

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11
Q

highest E half time?

A

fentanyl

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12
Q

Lowest E half time?

A

Remifentanil

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13
Q

Highest context sensitive half time?

A

Fentanyl

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14
Q

Lowest context senstive half time?

A

Remifantanil

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15
Q

Highest blood-brain equilibrium in minutes?

A

Fentanyl

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16
Q

lowest Blood-brain equilibrium in minutes

A

remifentanil

17
Q

What is the onset of opioid withdrawal for meperidine and fentanyl?

18
Q

What is the peak for opioid withdrawal for meperidine and fentanyl?

A

6-12 hours

19
Q

What is the duration for withdrawal for meperidine and fentanyl?

20
Q

What is the onset of opioid withdrawal for Morphine and heroin?

A

6-18 hours

21
Q

What is the peak for opioid withdrawal for morphine and heroin

A

36-72 hours

22
Q

What is the duration for withdrawal for morphine and heroin

23
Q

What is the onset of opioid withdrawal for methadone

A

24-48 hours

24
Q

What is the peak for opioid withdrawal for methadone

25
What is the duration of withdrawal for methadone?
6-7 weeks
26
What is the E 1/2 time of Propofol
0.5-1.5 hours