Drug Stats Flashcards
What drug has the highest % non-ionized?
Alfentanil
What drug has the Lowest % non-ionized?
Meperidine
What drug has the highest % protein binding?
Sufentanil
What drug has the lowest % protein binding?
Morphine
Highest clearance? mL/min
Remifantanil
Lowest clearance?
Alfentanil
Highest Vd?
Fentanyl
Lowest VD?
Alfentanil
Highest partition coefficeint?
sufentanil
Lowest partition coefficient
morphine
highest E half time?
fentanyl
Lowest E half time?
Remifentanil
Highest context sensitive half time?
Fentanyl
Lowest context senstive half time?
Remifantanil
Highest blood-brain equilibrium in minutes?
Fentanyl
lowest Blood-brain equilibrium in minutes
remifentanil
What is the onset of opioid withdrawal for meperidine and fentanyl?
2-6 hours
What is the peak for opioid withdrawal for meperidine and fentanyl?
6-12 hours
What is the duration for withdrawal for meperidine and fentanyl?
4-5 days
What is the onset of opioid withdrawal for Morphine and heroin?
6-18 hours
What is the peak for opioid withdrawal for morphine and heroin
36-72 hours
What is the duration for withdrawal for morphine and heroin
7-10 days
What is the onset of opioid withdrawal for methadone
24-48 hours
What is the peak for opioid withdrawal for methadone
3-21 days