Drug Slides - Week 3 (Part 2) - Exam 1

Question 1

What are the two branches of the Autonomic Nervous System?

Answer 1

1. sympathetic branch
2. parasympathetic branch

Question 2

Sympathetic response in r/t allergies or cold

Answer 2

constriction of arterioles, reducing thickness of mucosal layer

Question 3

parasympathetic response in r/t allergies or cold

Answer 3

dilation increasing thickness of mucosal layer

Question 4

what is a sympathomimetic?

Answer 4

(of a drug) producing physiological effects characteristic of sympathetic nervous system by promoting stimulation of sympathetic nerves

Question 5

Sympathothomimetc will therefore …

Answer 5

shrink the nasal mucosa, relieving nasal stuffiness with common cold

Question 6

what does an H1 receptor do?

Answer 6

histamine

widely distributed through out body (smooth muscle of airway, CV, endothelial cells, and lymphocytes) are associated with allergic reactions

Question 7

what does an H2 receptor do?

Answer 7

histamine; found in gastric mucosa, responsible for peptic ulcers

Question 8

Diphenhydramine: therapeutic class?

Answer 8

drug to treat allergies

Question 9

diphenhydramine: pharmacologic class?

Answer 9

H1-receptor antagonist; antihistamine

Question 10

Diphenhydramine: trade name?

Answer 10

benadryl

Question 11

Diphenhydramine: Actions and Uses

Answer 11

H1 receptor antagonist; treat minor allergy symptoms

Question 12

Diphenhydramine: Adverse effects

Answer 12

significant drowsiness

paradoxical CNS stimulation

anticholinergic effects: dry mouth, tachycardia, mild hypotension

Question 13

Diphenhydramine: contraindications

Answer 13

hypersensitity to drug; gi obstruction; asthma; hyperthyroidisim

Question 14

Diphenhydramine: Interactions. drug to drug

Answer 14

alcohol, opioids increase sedation

hyperintensive crisis

Question 15

Diphenhydramine: lab tests

Answer 15

discontinued 4 days prior to skin allergy test, false negative

Question 16

Fluticasone: theraputic class?

Answer 16

drug for allergic rhinitis

Question 17

fluticasone pharmacologic class?

Answer 17

intranasal corticosteroid

Question 18

Fluticasone: actions and uses

Answer 18

treat seasonal allergic rhinitis; decrease local inflammation in nasal passages

Question 19

Fluticasone: Adverse Effects

Answer 19

rare; nasal irritation; nose bleed; headache

Question 20

Fluticasone: interactions drug to drug

Answer 20

increased nasal irritation

Question 21

Oxymetazoline therapeutic class

Answer 21

nasal dicongestant

Question 22

oxymetazoline pharmacologic class

Answer 22

sympathomimetic

Question 23

Oxymetazoline contraindicaitons

Answer 23

thyroid disorders, hypertension, diabetes, heart disease

Question 24

oxymetazoline: actions and uses

Answer 24

activates alpha-adrenergic receptors in the sympathetic nervous system; nasal arterioles to constric, drying mucous membranes

Question 25

oxymetazoline: trade name

Answer 25

afrin

Question 26

oxymetazoline: adverse effects

Answer 26

rebound congestion; minor stinging, dryness;

Question 27

Dextromethorphan: trade name

Answer 27

delsym, robitussin dm

Question 28

dextromethorphan: therapeutic class

Answer 28

cough supressant

Question 29

dextromethorphan pharmacologic class

Answer 29

drug for increasing cough threshold

Question 30

dextromethorphan: actions and uses

Answer 30

nonopioid drug component in many otc severe cold and flu preparations

rapid onset of action.

Question 31

dextromethorphan: adverse effects

Answer 31

rare; dizzy; drowsy, gi upset; cns toxicity

Question 32

dextromethorphan: interactions drug to drug

Answer 32

excitation, hallucinations, hyperpyrexia, sedation

Question 33

dextromethorphan: contraindicaitons

Answer 33

treatment of chronic cough

children under 6 years old