Drug Side Effects Flashcards

1
Q

Coronary vasospasm

A

Cocaine
Amphetamines
Tristan’s
Ergotamine

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2
Q

Dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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3
Q

Torsades de pointes

A
Potassium channel blockers (class III)
Sodium channel blockers (class IA)
Macrolides
Haloperidol
Chloroquine
Protease inhibitors
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4
Q

Thrombocytopenia

A

Heparin

Cimetidine (H2 blockers)

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5
Q

Agranulocytosis

A

Clozapine
Carbamazepine
Colchicine
PTU, Methimazole, Dapsone

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6
Q

Aplastic anemia

A
Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole
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7
Q

Gray baby syndrome

A

Chloramphenicol

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8
Q

Hemolysis in G6PD deficiency

A
Isoniazid
Sulfonamides
Primaquine
Aspirin (high dose)
Ibuprofen
Nitrofurantoin 
Dapsone
Fava beans
Naphthalene
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9
Q

Thrombosis

A

Oral contraceptives

Esp. Smoker > 35 years old

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10
Q

Pulmonary fibrosis

A

Amiodarone
Bleomycin
Busulfan

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11
Q

Cough

A

ACE inhibitors

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12
Q

Pseudomembranous colitis

A

Clindamycin

Amoxicillin/ampicillin

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13
Q

Hepatic necrosis

A

Halothane
Acetaminophen
Valproic acid
Amanita phalloides

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14
Q

Hepatitis

A

Isoniazid

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15
Q

Tertiary adrenal insufficiency

A

Corticosteroid withdrawal

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16
Q

Gynecomastia

A
Spironolactone
THC (marijuana)
Alcohol chronic use
Cimetidine 
Ketoconazole 
Estrogens
Digoxin
17
Q

Hot flashes

A

Tamoxifen

Clomiphene

18
Q

Hypothyroidism

A

Amiodarone
Lithium
Sulfonamides

19
Q

Gout

A

Diuretics (loop and thiazides)
Niacin
Cyclosporine
Pyrazinamide

20
Q

Gingival hyperplasia

A

Phenytoin

Verapamil

21
Q

Osteoporosis

A

Corticosteroids

Heparin

22
Q

Photosensitivity

A

Sulfonamides
Amiodarone
Tetracycline

23
Q

Stevens-Johnson syndrome

A
Carbamazepine
Lamotrigine
Allopurinol 
Phenytoin
Phenobarbital
Penicillin
Ethosuximide
RASH
Sulfa drugs
24
Q

Drug-induced lupus

A
Sulfonamide so
Hydralazine
Isoniazid 
Procainamide 
Phenytoin
25
Q

Tendinitis/cartilage damage

A

Fluoroquinolones

26
Q

Interstitial nephritis

A

NSAIDs
Furosemide
Antibiotics

27
Q

Diabetes insipidus

A

Lithium

Demeclocycline

28
Q

Fanconi syndrome

A

Tetracycline

Heavy metal exposure

29
Q

Hemorrhagic cystitis

A

Cyclophosphamide

Ifosfamide

30
Q

Parkinson-like syndrome

A

Metoclopramide
Antipsychotics
Reserpine

31
Q

Cinchonism

A

Quinidine

Quinine

32
Q

Seizures

A
Buproprion 
Imipenem/cilastatin
Isoniazid
Tramadol
Metoclopramide
Benzodiazepine/alcohol withdrawal
33
Q

Tarditive dyskinesia

A

Antipsychotics

Metoclopramide

34
Q

Disulfiram-like reaction

A
Metronidazole 
Certain cephalosporins
Procarbazine
First gen sulfonylureas
Disulfiram
35
Q

Nephrotoxicity + neurotoxicity

A

Aminoglycosides
Cisplatin
Polymixins

36
Q

Nephrotoxicity + otoxicity

A

Aminoglycosides
Vancomycin
Loop diuretics
Cisplatin

37
Q

Anticholinergic effects

A

Atropine
Trycyclic antidepressants
H1 blockers
Low-potency neuroleptics

38
Q

Flushing

A

Vancomycin
Niacin
Adenosine
Dihydropyridine calcium channel blockers