Drug Side Effects

Question 1

Coronary vasospasm

Answer 1

Cocaine
Amphetamines
Tristan’s
Ergotamine

Question 2

Dilated cardiomyopathy

Answer 2

Doxorubicin

Daunorubicin

Question 3

Torsades de pointes

Answer 3

Potassium channel blockers (class III)
Sodium channel blockers (class IA)
Macrolides
Haloperidol
Chloroquine
Protease inhibitors

Question 4

Thrombocytopenia

Answer 4

Heparin

Cimetidine (H2 blockers)

Question 5

Agranulocytosis

Answer 5

Clozapine
Carbamazepine
Colchicine
PTU, Methimazole, Dapsone

Question 6

Aplastic anemia

Answer 6

Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole

Question 7

Gray baby syndrome

Answer 7

Chloramphenicol

Question 8

Hemolysis in G6PD deficiency

Answer 8

Isoniazid
Sulfonamides
Primaquine
Aspirin (high dose)
Ibuprofen
Nitrofurantoin 
Dapsone
Fava beans
Naphthalene

Question 9

Thrombosis

Answer 9

Oral contraceptives

Esp. Smoker > 35 years old

Question 10

Pulmonary fibrosis

Answer 10

Amiodarone
Bleomycin
Busulfan

Question 11

Cough

Answer 11

ACE inhibitors

Question 12

Pseudomembranous colitis

Answer 12

Clindamycin

Amoxicillin/ampicillin

Question 13

Hepatic necrosis

Answer 13

Halothane
Acetaminophen
Valproic acid
Amanita phalloides

Question 14

Hepatitis

Answer 14

Isoniazid

Question 15

Tertiary adrenal insufficiency

Answer 15

Corticosteroid withdrawal

Question 16

Gynecomastia

Answer 16

Spironolactone
THC (marijuana)
Alcohol chronic use
Cimetidine 
Ketoconazole 
Estrogens
Digoxin

Question 17

Hot flashes

Answer 17

Tamoxifen

Clomiphene

Question 18

Hypothyroidism

Answer 18

Amiodarone
Lithium
Sulfonamides

Question 19

Gout

Answer 19

Diuretics (loop and thiazides)
Niacin
Cyclosporine
Pyrazinamide

Question 20

Gingival hyperplasia

Answer 20

Phenytoin

Verapamil

Question 21

Osteoporosis

Answer 21

Corticosteroids

Heparin

Question 22

Photosensitivity

Answer 22

Sulfonamides
Amiodarone
Tetracycline

Question 23

Stevens-Johnson syndrome

Answer 23

Carbamazepine
Lamotrigine
Allopurinol 
Phenytoin
Phenobarbital
Penicillin
Ethosuximide
RASH
Sulfa drugs

Question 24

Drug-induced lupus

Answer 24

Sulfonamide so
Hydralazine
Isoniazid 
Procainamide 
Phenytoin

Question 25

Tendinitis/cartilage damage

Answer 25

Fluoroquinolones

Question 26

Interstitial nephritis

Answer 26

NSAIDs Furosemide Antibiotics

Question 27

Diabetes insipidus

Answer 27

Lithium | Demeclocycline

Question 28

Fanconi syndrome

Answer 28

Tetracycline | Heavy metal exposure

Question 29

Hemorrhagic cystitis

Answer 29

Cyclophosphamide | Ifosfamide

Question 30

Parkinson-like syndrome

Answer 30

Metoclopramide Antipsychotics Reserpine

Question 31

Cinchonism

Answer 31

Quinidine | Quinine

Question 32

Seizures

Answer 32

``` Buproprion Imipenem/cilastatin Isoniazid Tramadol Metoclopramide Benzodiazepine/alcohol withdrawal ```

Question 33

Tarditive dyskinesia

Answer 33

Antipsychotics | Metoclopramide

Question 34

Disulfiram-like reaction

Answer 34

``` Metronidazole Certain cephalosporins Procarbazine First gen sulfonylureas Disulfiram ```

Question 35

Nephrotoxicity + neurotoxicity

Answer 35

Aminoglycosides Cisplatin Polymixins

Question 36

Nephrotoxicity + otoxicity

Answer 36

Aminoglycosides Vancomycin Loop diuretics Cisplatin

Question 37

Anticholinergic effects

Answer 37

Atropine Trycyclic antidepressants H1 blockers Low-potency neuroleptics

Question 38

Flushing

Answer 38

Vancomycin Niacin Adenosine Dihydropyridine calcium channel blockers