Drug References Flashcards

1
Q

PIs do not include…

A

off-label uses or drug costs

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2
Q

package insert locations

A

DailyMed, Drugs@FDA, drug manufacturer’s website, attached to physical product

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3
Q

BOXED WARNING

A

strictest warnings; alerts prescribers to risk of death or permanent diability

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4
Q

general drug information sources

A
  • American Hospital Formulary Service (AFHS)
  • Clinical Pharmacology
  • Epocrates/Epocrates +
  • Facts & Comparisons eAnswers
  • Lexicomp
  • Micromedex
  • Prescriber’s Digital Reference (mobilePDR)
  • PubChem (NLM)
  • Drugs.com
  • RxList
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5
Q

What drug information resources offer IV drug compatibility?

A
  • AHFS
  • Clinical Pharmacology (via Trissel’s)
  • Facts & Comparisons eAnswers (via Trissel’s)
  • Lexicomp (via Trissel’s)
  • Micromedex (via Trissel’s)
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6
Q

What drug information sources provide drug-pill ID?

A
  • Clinical Pharmacology
  • Drugs.com
  • Epocrates/Epocrates+
  • Facts & Comparisons eAnswers
  • Lexicomp (Lexi-Drug ID)
  • Micromedex (IDENTIDEX)
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7
Q

What drug information sources provide pricing?

A
  • Clinical Pharmacology
  • Drugs.com
  • Epocrates/Epocrates+
  • Lexicomp
  • Micromedex (Red Book)
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8
Q

What drug information resources provide international drug names?

A
  • AHFS (via USP Dictionary of USAN and Internation Drug Names)
  • Clinical Pharmacology (via Index Nominum)
  • Drugs.com
  • Facts & Comparisons eAnswers (via Martindale)
  • Lexicomp (via Martindale)
  • Micromedex (via Martindale, Index Nominum, & others)
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9
Q

What does Pharmacist’s Letter include?

A

Subscribers receive a monthly newsletter & have access to:
- new drug approvals, drug withdrawals, new dosage forms, first-time generics
- charts (e.g., drug class comparisons, disease state treatment summaries)
- patient education summaries & patient flyers
- CE
- training materials for techs & interns

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10
Q

guidelines for anticoagulation

A

Guidelines from the American College of Chest Physicians (known as CHEST guidelines):
- Stroke Prevention in AFib
- Venous Thromboembolism

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11
Q

guidelines for CV diseases

A

ACC/AHA:
- ACS
- AFib
- HF
- High Cholesterol
- HTN

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12
Q

guidelines for diabetes

A

AACE, ADA

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13
Q

guidelines for infectious diseases

A
  • IDSA
  • HIV/AIDS: US Dept. of Health and Human Services (ClinicalInfo.HIV.gov)
  • STIs: CDC
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14
Q

guidelines for oncology

A

American Society of Clinical Oncology (ASCO), National Comprehensive Cancer Network (NCCN)

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15
Q

guidelines for pediatrics

A

American Academy of Pediatrics (AAP)

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16
Q

guidelines for pregnancy/women’s health

A

ACOG

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17
Q

guidelines for psych conditions

A

American Psychiatric Association (APA) Diagnostic and Statistical Manual of Mental disorders, 5th Edition (DSM-5)

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18
Q

guidelines for asthma

A

GINA and National Heart, Lung, and Blood Institute (NHLBI)

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19
Q

guidelines for COPD

A

GOLD

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20
Q

guidelines for renal disease

A

KDIGO

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21
Q

guidelines for vaccines

A

ACIP, CDC

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22
Q

references for adverse reactions

A

ASHP’s Drug-Induced Diseases: Prevention, Detection, and Management

FDAble - FDA searchable database
- MedWatch: FDA’s Adverse Event Reporting System (FAERS)
- Vaccine Adverse Event Reporting System (VAERS)
- etc.

Meyler’s Side Effects of Drugs

23
Q

references for compounding & pharmaceutics

A
  • Allen’s The Art, Science, and Technology of Pharmaceutical Compounding
  • ASHP Guidelines on Compounding Sterile Preparations
  • Handbook of Pharmaceutical Excipients
  • Safety Data Sheets (SDS)
  • Merck Index: An Encyclopedia of Chemicals, Drugs, & Biologicals
  • Remington: The Science and Practice of Pharmacy
  • Trissel’s Stability of Compounded Formulations
  • USP Compounding Compendium: USP 795, 797, 800, USP-NF
  • etc.
24
Q

specialty references for drug interactions

A

Hansten and Horn’s
Drug Interaction Facts: Facts & Comparisons

25
Q

references for drug pricing

A

Red Book (Micromedex)
Medi-Span Price Rx

26
Q

references for drug shrotages

A
  • ASHP Current Drug Shortages
  • FDA Drug Shortages
  • CDC Current Vaccine Shortages & Delays
  • AHFS CDI
27
Q

references for drug subsitution

A
  • FDA’s Orange Book - therapeutic equivalence
  • FDA’s Purple Book - biosimilarity or interchangeability
28
Q

specialty references for geriatrics

A
  • American Geriatric Society (AGS) Beers Criteria
  • Others: ASHP’s Fundamentals of Geriatric Pharmacotherapy, Geriatric Dosage Handbook (Lexicomp)
29
Q

references for immunizations (adult and peds)

A
  • CDC Advisory Committee on immunization Practices (ACIP) -> updates published in Morbidity and Mortality Weekly Report (MMWR)
  • CDC Pink Book
  • Immunization Action Coalition

Others: APhA Immunization Center; Vaccines, Blood & Biologics (FDA)

30
Q

specialty references for infectious diseases

A

IDSA, Sanford Guide to Antimicrobial Therapy

31
Q

specialty references for HIV

A

HIVInfo.NIH.gov

Others: Sanford Guide to HIV/AIDS Therapy, John Hopkins ABX and HIV guides

32
Q

specialty references for travel medicine

A

World Health Organization (WHO)
CDC
- Yellow Book: for international travel
- Traveler’s Health

Others: ISTM, IAMAT

33
Q

specialty references for internation drug info

A
  • Index Nominum
  • Martindale
  • USP Dictionary of United States Adopted Names (USAN) and International Drug Names

Others: Drug Information Handbook with International Trade Names Index (Lexicomp), European Drug Index

34
Q

reference for investigational drugs

A

Clinicaltrials.gov (NIH)

35
Q

references for IV drug compatibility & stability

A
  • ASHP’s Handbook on Injectable Drugs
  • King Guide
  • Trissel’s 2 Clinical Pharmaceutics Database
36
Q

references for med safety

A
  • FDA MedWatch - report adverse events & med errors
  • ISMP - report med errors to ISMP Medication Errors Reporting Program (ISMP MERP)
  • NIOSH
  • FDA
37
Q

references for natural products/alternative medicine

A

Natural Medicines Database

Others: Dietary Supplements Label Database (NIH), USP Dietary Supplements Compendium

38
Q

references for overdoses, poisoning, & toxicology

A
  • Lexi-Tox (Lexicomp)
  • Micromedex Toxicology Management (previously POISONDEX)
  • TOXLINE in PubMed

Others: Goldfrank’s Toxicologic Emergencies, State Poison Control Center, American Association of Poison Control Centers

39
Q

specialty references for pharmacology

A

Goodman and Gilman’s, Katzung’s Basic and Clinical Pharmacology

39
Q

references for pregnancy & lactation

A

Brigg’s, CDC, Hale’s, LactMed, Micromedex, MotherToBaby

39
Q

references for pediatrics

A
  • NeoFax (Micromedex)
  • Pediatric & Neonatal Dosage Handbook (Lexicomp)
  • Red Book: Report of the Committee on Infectious Diseases (AAP)
  • Harriet Lane Handbook
  • AAP

Others: ASHP’s Pediatric Injectable Drugs, Nelson, PPA’s KIDs list

40
Q

references for regulatory & business development

A

FDA Center for Drug Evaluation and Research (CDER), Pink Sheet

41
Q

references for therapeutics & disease management

A
  • DiPiro’s
  • Handbook of Nonprescription Drugs
  • Koda-Kimble’s Applied Therapeutics
  • The Merck Manual
  • UpToDate

Others: CDC, Harrison’s Principles of Internal Medicine, Medscape

42
Q

veterinary reference

A

Plumb’s Veterinary Drug Handbook

43
Q

What rating in the Orange Book indicates generic substitution is acceptable?

A

AB rating indicates therapeutic equivalence

44
Q

Pink Book (CDC)

A

info on epidemiology & vaccine-preventable diseases

45
Q

Pink Sheet (Pharma Intelligence)

A

news reports on regulatory, legislative, legal, & business developments

46
Q

Red Book, Pharmacy

A

drug pricing information

47
Q

Red Book, Pediatrics (AAP)

A

summaries of pediatric infectious diseases, antimicrobial tx, & vaccinations

48
Q

Yellow Book (CDC)

A

info on the health risks of international travel, required vaccines, & prophylaxis meds

49
Q

Green Book (FDA)

A

info on approved animal drug products

50
Q

common research databases

A
  • PubMed: accesses MEDLINE (journal articles), free service from NLM
  • Cochrane Library: evidence-based information to guide clinical decision making; database of Cochrane Systematic Reviews
51
Q

resources that are patient-friendly

A
  • CDC has a symptom checker & provides info on ID, immunizations, & traveler’s health
  • Drugs.com and RxList
  • Mayo Clinic
  • Medline Plus (from NLM)
  • WebMD has pill identifier & interaction checker
  • etc.