Drug Reactions

Question 1

Coronary vasospasm (3)

Answer 1

Cocaine
Sumatriptan
Ergot alkaloids

Question 2

Cutaneous flushing (4)

Answer 2

VANC

• Vancomycin
• Adenosine
• Niacin
• Ca channel blockers

Question 3

Dilated cardiomyopathy (2)

Answer 3

Doxorubicin

Daunorubicin

Question 4

Torsades de pointes (2)

Answer 4

Class III (sotalol)
Class IA (quinidine)

Question 5

Agranulocytosis (6)

Answer 5

Agranulocytosis Could Certainly Cause Pretty Major Damage

-Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone

Question 6

Aplastic anemia (5)

Answer 6

Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole

Question 7

Direct Coombs-positive hemolytic anemia (2)

Answer 7

Penicillin

Methyldopa

Question 8

Gray baby syndrome

Answer 8

Chloramphenicol

Question 9

Hemolysis in G6PD (6)

Answer 9

Hemolysis IS PAIN

• Isoniazid
• Sulfonamides
• Primaquine
• Aspirin
• Ibuprofen
• Nitrufurantoin

Question 10

Megaloblastic anemia

Answer 10

Having a blast with PMS

• Phenytoin
• Methotrexate
• Sulfa drugs

Question 11

Cough

Answer 11

ACE inhibitors

-(ARBs like losartan - no cough)

Question 12

Pulmonary fibrosis (3)

Answer 12

It’s hard to BLAB with pulmonary fibrosis

• Bleomycin
• Amiodarone
• Busulfan

Question 13

Acute cholestatic hepatitis

Answer 13

Erythromycin

Question 14

Hepatic necrosis (4)

Answer 14

Liver HAVAc

• Halothane
• Amanita phalloides
• Valproic acid
• Acetaminophen

Question 15

Hepatitis

Answer 15

INH

Question 16

Pseudomembranous colitis (2)

Answer 16

Clindamycin

Ampicillin

Question 17

Adrenocortical insufficiency

Answer 17

Glucocoritcoid withdrawal (HPA suppression)

Question 18

Gynecomastia (5)

Answer 18

Some Drugs Create Awkward Knockers

• Spironolactone
• Digitalis
• Cimetidine
• Alcohol
• Ketoconazole

Question 19

Hot flashes (2)

Answer 19

Tamoxifen

Clomiphene

Question 20

Hyperglycemia (5)

Answer 20

Niacin
Tacrolimus
Protease inhibitors
HydrochloroThiazide
Corticosteroids

Question 21

Hypothyroidism (3)

Answer 21

Lithium
Amiodarone
Sulfonamides

Question 22

Fat redistribution (2)

Answer 22

Glucocorticoids

Protease inhibitors

Question 23

Gingival hyperplasia (2)

Answer 23

Phenytoin

Verapamil

Question 24

Gout (4)

Answer 24

Furosemide
Thiazides
Niacin
Cyclosporine

Question 25

Myopathies (8)

Answer 25

Fish N CHIPS Give you myopathies - Fibrates - Niacin - Colchicine - Hydroxychloroquine - Interferon-a - Penicillamine - Statins - Glucocorticoids

Question 26

Osteoporosis (2)

Answer 26

Corticsteroids | Heparin

Question 27

Photosensitivity (3)

Answer 27

SAT for a photo - Sulfonamides - Amiodarone - Tetracycline

Question 28

Rash - SJS - (8)

Answer 28

Bad rash after a PEC SLAPP - Penicillin, Ethosuximide - Carbamazepine, Sulfa drugs - Lamotrigine, Allopurinol - Phenytoin, Phenobarbital

Question 29

SLE-like syndrome (4)

Answer 29

It's not HIPP to have lupus - Hydralazine - INH - Procainamide - Phenytoin

Question 30

Tendonitis, cartilage damage

Answer 30

Fluoroquinolones

Question 31

Diabetes insipidus (2)

Answer 31

Lithium | Demeclocycline

Question 32

Fanconi's syndrome

Answer 32

Expired tetracycline

Question 33

Hemorrhagic cystitis (2)

Answer 33

Cyclophosphamide | Isosfamide (prevent with Mesna)

Question 34

Cinchonism

Answer 34

Quinidine

Question 35

Parkinson-like syndrome (3)

Answer 35

Antipsychotics Reserpine Metoclopramide

Question 36

Seizures (6)

Answer 36

With seizures, I BITE My tongue - Isoniazid - Bupropion - Imepenem/cilastatin - Tramadol - Enflurane - Metoclopramide

Question 37

Antimuscarinic (4)

Answer 37

Atropine TCAs H1-blockers Neuroleptics

Question 38

Disulfiram-like reaction (4)

Answer 38

Metronidazole Cephalosporins (some) Procarbazine 1st gen sulfonylureas

Question 39

Nephrotoxicity/ototoxicity (4)

Answer 39

Aminoglycosides Vancomycin Loop diuretics Cisplatin