Drug Quiz #4: Indications

Question 1

Sugammadex (Bridion)

Answer 1

Routine reversal of rocuronium- or vecuronium-induced blockade, immediate reversal of rocuronium-induced blockade

Question 2

Prothrombin Complex Concentrate (Human) [(Factors II, VII, IX, X), Protein C, and Protein S] (Kcentra, Balfaxar)

Answer 2

Life-threatening hemorrhage associated with direct factor Xa inhibitor or direct thrombin inhibitor, perioperative coagulopathy, reversal of oral direct factor Xa inhibitor in patients who require urgent procedure, reversal of vitamin K antagonist in patients with acute major bleeding or need for an urgent surgery/invasive procedure

Question 3

Bupivacaine (Liposomal) (Exparel)

Answer 3

Postsurgical analgesia

Question 4

Dexmedetomidine (Precedex)

Answer 4

Maintenance of general anesthesia, procedural sedation or monitored anesthesia care, mechanically ventilated patients in the ICU, sedation

Question 5

Abciximab (Reopro)

Answer 5

PCI (myocardial ischemia ppx, refractory unstable angina), acute myocardial infarction- cardiogenic shock. acute arterial thrombosis, myocardial infarction

Question 6

Tirofiban (Aggrastat)

Answer 6

Acute coronary syndrome

Question 7

Cocaine (C-Topical, Goprelto, Numbrino)

Answer 7

Anesthesia

Question 8

Mannitol (Osmitrol, Resectisol)

Answer 8

Kidney transplant- intraoperative volume optimization, transurethral irrigation, intracranial pressure reduction, intraoccqular pressure reduction

Question 9

Tranexamic Acid (Cyklokapron; Lysteda)

Answer 9

Perioperative prevention of blood loss and transfusion, trauma-associated hemorrhage or traumatic brain injury, dental procedures in patients on oral anticoagulant therapy

Question 10

Ketamine (Ketalar)

Answer 10

General anesthesia, procedural sedation, mechanically ventilated patients in the ICU- analgesia/sedation/agitation, RSI induction outside the operating room, analgesia- subanesthetic dosing