Drug Quiz 4 Flashcards

1
Q
hydrocodone bitartrate with acetaminophen
Brand?
TC?
MOA?
AE?
A

Brand: Lortab, Vicodin, Norco
TC: opioid analgesi
MOA: acetaminophen - inhibiting prostaglandin synthesis; hydrocodone - opioid analgesic, action on central opiate receptors
AE: constipation, dizziness, drowsiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
oxycodone with acetaminophen
Brand?
TC?
MOA?
AE?
A

Brand: Percocet, Roxicet, Endocet
TC: opioid analgesic
MOA: acetaminophen - inhibiting prostaglandin synthesis, opioid analgesic, action on central opiate receptors
AE: constipation, dizziness, drowsiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
oxycodone
Brand?
TC?
MOA?
AE?
A

Brand: Oxycontin, Roxicodone
TC: opioid analgesic
MOA: opioid analgesic, action central opiate receptors
AE: constipation, somnolence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
morphine (extended release)
Brand?
TC?
MOA?
AE?
A

Brand: MS Contin
TC: opioid analgesic
MOA: opioid analgesic, action on central opiate receptors
AE: constipation, lightheadedness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
fentanyl (transdermal)
Brand?
TC?
MOA?
AE?
A

Brand: Duragesic
TC: opioid analgesic
MOA: opioid analgesic, action on central opiate receptors (u)
AE: hypoventilation, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
acetaminophen with codeine
Brand?
TC?
MOA?
AE?
A

Brand: Tylenol (with Codeine)
TC: opioid analgesic
MOA: acetaminophen - inhibiting prostaglandin synthesis, Codeine - weak opioid agonist, (u) opiate receptors
AE: constipation, dizziness, drowsiness, sweating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
hydromorphone
Brand?
TC?
MOA?
AE?
A

Brand: Dilaudid
TC: opioid analgesic
MOA: opioid agonist, action on central opiate receptors
AE: constipation, respiratory depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
methadone
Brand?
TC?
MOA?
AE?
A

Brand: Methadone
TC: opioid analgesic
MOA: opioid analgesic, action on central opiate receptors
AE: dizziness, drowsiness, lightheadedness, sweating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
oxymorphone
Brand?
TC?
MOA?
AE?
A

Brand: Opana
TC: opioid analgesic
MOA: opioid analgesic, action on central opiate receptors
AE: constipation, respiratory depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
buprenorphine with naloxone
Brand?
TC?
MOA?
AE?
A

Brand: Suboxone
TC: opioid dependence agent
MOA: buprenorphine - partial opioid agonist MU/antagonist KAPPA. naloxone - antagonist at mu-opioid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q
donepezil
Brand?
TC?
MOA?
AE?
A

Brand: Aricept
TC: Alzheimer’s dementia agent
MOA: acetylcholinesterase inhibitor (increase amount of acetylcholine available at cholinergic synapses)
AE: Steven Johnsons Syndrome, QTC prolongation, rhabdomyolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
memantine
Brand?
TC?
MOA?
AE?
A

Brand: Namenda
TC: Alzheimer’s dementia agent
MOA: NMDA receptor antagonist (weak to moderate)
AE: dizziness, headache, hallucination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q
benztropine
Brand?
TC?
MOA?
AE?
A

Brand: Cogentin
TC: antiparkinson agent
MOA: inhibitor of both cholinergic/histamine receptors
AE: dry mouth, blurry vision, numbness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q
carbidopa with levodopa
Brand?
TC?
MOA?
AE?
A

Brand: Sinemet (CR)
TC: antiparkinson agent
MOA: carbidopa - inhibits dopa-decarboxylase, (increase Levodopa levels), levodopa - converts to dopamine
AE: dystonia/involuntary movements, dementia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
pramipexole
Brand?
TC?
MOA?
AE?
A

Brand: Mirapex
TC: antiparkinson agent
MOA: nonergot dopamine receptor agonist
AE: dizziness, somnolence, asthenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
ropinirole
Brand?
TC?
MOA?
AE?
A

Brand: Requip (XL)
TC: antiparkinson agent
MOA: dopamine D2/D3 agonist
AE: somnolence, dizziness, syncope

17
Q
aripiprazole
Brand?
TC?
MOA?
AE?
A

Brand: Abilify
TC: antipsychotic
MOA: unknown (agonist of D2 and 5HT1A/antagonist of 5-HT2A)
AE: tardive dyskinesia, anxiety

18
Q
lurasidone
Brand?
TC?
MOA?
AE?
A

Brand: Latuda
TC: antipsychotic
MOA: unknown(antagonism of dopamine D2 and serotonin 5HT2 receptors)
AE: neuroleptic malignant syndrome, tardive dyskinesia

19
Q
olanzapine
Brand?
TC?
MOA?
AE?
A

Brand: Zyprexa
TC: antipsycotic
MOA: unknown (antagonism of dopamine D2 and serotonin 5HT2 receptors), inhibitor of muscarinic/histamine/adrenergic alpha 1 receptors
AE: somnolence, agitation, insomnia

20
Q
quetiapine
Brand?
TC?
MOA?
AE?
A

Brand: Seroquel
TC: antipsychotic
MOA: multiple neurotransmitter antagonist (5HT1, 5HT2, dopamine 1/D2, histamine 1, adrenergic alpha 1/2 receptors)
AE: somnolence, hypotension, dry mouth

21
Q
risperidone
Brand?
TC?
MOA?
AE?
A

Brand: Risperdal
TC: antipsychotic
MOA: unknown (antagonism of dopamine D2 and serotonin 5HT2 receptors)
AE: extrapyramidal symptoms, tachycardia, priapism, rash

22
Q
ziprasidone
Brand?
TC?
MOA?
AE?
A

Brand: Geodon
TC: antipsychotic
MOA: unknown (antagonism of dopamine D2 and serotonin 5HT2 receptors)
AE: drowsiness, heart arrhythmias, dizziness

23
Q
amphetamine and dextroamphetamine salts
Brand?
TC?
MOA?
AE?
A

Brand: Adderall (XR)
TC: CNS agent for ADHD
MOA: unknown (CNS stimulation on adrenergic receptors, releasing NE)
AE: restlessness, insomnia

24
Q
methylphenidate (IR and ER)
Brand?
TC?
MOA?
AE?
A

Brand: Ritalin, Methylin, Metadate, Concerta
TC: CNS agent for ADHD
MOA: activates the brain stem arousal system and cortex
AE: nervousness, insomnia, palpitations

25
Q
dexmethylphenidate
Brand?
TC?
MOA?
AE?
A

Brand: Focalin (XR)
TC: CNS agent for ADHD
MOA: unknown (central nervous system stimulant)
AE: dry mouth, anxiety, insomnia

26
Q
lisdexamfetamine
Brand?
TC?
MOA?
AE?
A

Brand: Vyvanse
TC: CNS agent for ADHD
MOA: unknown (CNS stimulation on adrenergic receptors, releasing NE)
AE: decreased appetite, insomnia, dry mouth

27
Q
atomoxetine
Brand?
TC?
MOA?
AE?
A

Brand: Strattera
TC: CNS agent for ADHD
MOA: unknown (inhibition of pre-synaptic norepinephrine transporter)
AE: mood swings, dry mouth, insomnia

28
Q
guanfacine
Brand?
TC?
MOA?
AE?
A

Brand: Intuniv
TC: antihypertensive/ADHD
MOA: stimulates central alpha-2 adrenergic receptors
AE: drowsiness, weakness, dry mouth