Drug Profiles Flashcards
Adenosine/Adenocard classification
Antiarrhythmic
Endogenous Nucleoside
Adenosine/Adenocard MOA
Slows conduction time through AV node
slows sinus rate
Adenosine/Adenocard Indications
SVT.
Wide complex tachycardia of uncertain origin unresponsive to lidocaine.
Adenosine/Adenocard contraindications
Sick Sinus Syndrome.
2nd/3rd* AV blocks - except in patients with pacemakers.
Known A-fib/A-flutter.
Pregnancy.
Adenosine/Adenocard adverse reactions
Transient dysrhythmias (asystole, bradycardia, PVC’s, V-tach)
Adenosine/Adenocard routes of administration
Recommended IV site is antecubital fossa.
IV/IO only.
Adenosine/Adenocard Adult dose
Initial: 12mg Rapid IV bolus over 1-3 sec followed by 20cc NS flush.
Repeat dose: 1x repeat only. Same as initial dose.
Adenosine/Adenocard Pediatric dose
Initial: 0.1mg/kg Rapid IV bolus with 2-3cc NS flush.
Repeat: 1x repeat only. .2mg/kg Rapid IV bolus with 2-3cc NS flush.
Adenosine/Adenocard onset of action
seconds
Adenosine/Adenocard special notes
Dysrhythmias may recur and appear in 55% of patients, lasting for a few seconds. Use cautiously in patients on theophylline and related methylxanthines, dipyridomole (Persantine), or carbamazepine (Tegretol).
Adenosine/Adenocard forms/packaging
Flip top vials 6mg/2ml (3mg per ml)
Prefilled syringe 6mg/2ml (3mg per ml)
Prefilled syringe 12mg/4ml
Adenosine/Adenocard AZ drug box supply
Paramedics: 5-6 vials (2+ 12mg doses)
Albuterol Sulfate/Proventil/Ventolin classification
Sympathomimetic
Brochodilator
Albuterol Sulfate/Proventil/Ventolin MOA
Stimulates Beta2 receptors in the smooth muscle of the bronchial tree
Albuterol Sulfate/Proventil/Ventolin Indications
Bronchospasm
Albuterol Sulfate/Proventil/Ventolin contraindications
Use caution in patients with diabetes, hyperthyroidism, and cerebrovascular disease
Tricyclic antidepressants
MAO inhibitors
Albuterol Sulfate/Proventil/Ventolin Adverse reactions
dysrhythmias tachycardia tremors nervousness N/V
Albuterol Sulfate/Proventil/Ventolin adult dose
2.5mg of premixed solution for inhalation (0.083%) via SVN. May repeat as needed.
Albuterol Sulfate/Proventil/Ventolin pediatric dose
<40lbs, administer half of 0.083% premixed solution by adding 1-1.5ml NS to make 2.5-3cc and administer via SVN
Albuterol Sulfate/Proventil/Ventolin route of administration
nebulized via mouth piece or in-line mask, or nebulized through ET/NT in-line
Albuterol Sulfate/Proventil/Ventolin onset of action
5-15 minutes
Albuterol Sulfate/Proventil/Ventolin AZ drug box supply
Paramedics: 2-6 independant doses
Albuterol Sulfate/Proventil/Ventolin dosage forms/packaging
2.5mg albuterol premixed solution tube
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC classification
analgesic (pain relief)
antipyretic (fever reducing)
anti-inflammatory
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC MOA
aspirin blocks thromboxane A2 (a potent platelet aggregate) and decreases platelet aggregation
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC indications
chest pain
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC contraindications
bleeding ulcer
hemorrhagic states
hemophilia
known hypersensitivity to salicylates or other non-steroidal anti-inflammatories
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC adverse reactions
anaphylactic reaction in sensitive patients have occurred
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC adult dose
324mg PO (4 x 81mg pediatric chewable tabs)
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC pediatric dose
not recommended for peds
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC onset of action
20-30 minutes
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC special notes
baby ASA is heat and light sensitive. The odor of acetic acid (vinegar-like smell) indicates degradation of product.
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC dosage forms
81mg-325mg tablets
acetylsalicylic acid/aspirin/ASA/Bufferin/Anacin/APC AZ drug box supply
Paramedics: 36 to 100 tablets
atropine sulfate/Atropine classification
parasympatholytic (decreases parasympathetic nervous system - the PSNS slows heart rate among other things)
antimuscarinic
parasympathetic antagonist
atropine sulfate/Atropine MOA
competitively blocks acetylcholine (Ach) at muscarinic receptor sites
atropine sulfate/Atropine indications
symptomatic bradycardia (sinus, junctional, & AV blocks) Asystole (no longer in AHA or PFD guidelines) PEA (no longer in AHA or PFD guidelines) Organophosphate/Cholinergic poisonings
atropine sulfate/Atropine contraindications
glaucoma
acute narrow angle glaucoma (relative contraindication)
atropine sulfate/Atropine adverse reactions
tachydysrhythmias
exacerbation of glaucoma
precipitation of myocardial ischemia (insufficient blood flow to the heart)
atropine sulfate/Atropine adult dose
Symptomatic bradycardia: 0.5-1.0mg Rapid IVP every 3-5 minutes, to a total dose of 3mg.
Cholinergic/Organophosphate poisoning: 2.0-5.0mg IV. May repeat in 5 minutes. No max dose.
atropine sulfate/Atropine pediatric dose
Symptomatic bradycardia: 0.02mg/kg IV/IO.
May repeat once. Max dose: Child - 0.5mg. Adolescent - 1.0mg
atropine sulfate/Atropine routes of administration
IV/IO/ET
atropine sulfate/Atropine onset of action
1 minute
atropine sulfate/Atropine special notes
administering too small of doses or too slowly may result in paradoxical bradycardia.
Patient that describes their glaucoma as painful probably has acute narrow angle glaucoma.
atropine sulfate/Atropine dosage forms
1mg/10ml prefilled syringes
8mg/20ml multi-dose vial
atropine sulfate/Atropine AZ drug box supply
Paramedics: 4 x (1mg/10ml) prefilled syringes 1 x (8mg/20ml) multidose vial which is .4mg/ml.
ipratropium bromide/Atrovent classification
anticholinergic
bronchodilator
ipratropium bromide/Atrovent MOA
produces preferential dilation of the larger central airways
ipratropium bromide/Atrovent indications
bronchospasm
ipratropium bromide/Atrovent contraindications
hypersensitivity to ipratropium bromide or to atropine and its derivatives
ipratropium bromide/Atrovent adverse reactions
coughing sputum increase dizziness tremors nausea
ipratropium bromide/Atrovent administration notes
it is a safe and effective bronchodilator when used in conjunction with beta adrenergic bronchodilators (albuterol).
ipratropium bromide/Atrovent adult dose
2.5ml of a 0.02% solution via SVN may be used one time.