Drug Prefixes and Suffixes Flashcards

1
Q

liximab (GI)

A

monoclonal antibodies

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2
Q

peg (GI)

A

PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer

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3
Q

prazole (GI)

A

antiulcer agents (benzimidazole derivatives)

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4
Q

prost (GI)

A

prostaglandins

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5
Q

sal (GI)

A

anti-inflammatory agents (salicylic acid derivatives)

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6
Q

setron (GI)

A

serotonin 5-HT3 receptor antagonists

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7
Q

tidine (GI)

A

H2 receptor antagonists

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8
Q

ac (MSK)

A

anti-inflammatory agents (acetic acid derivatives)

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9
Q

adol (MSK)

A

analgesics (mixed opiate receptor agonists/antagonists)

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10
Q

coxib (MSK)

A

cyclooxygenase-2 inhibitors

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11
Q

dronate (MSK)

A

calcium metabolism regulators

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12
Q

icam (MSK)

A

anti-inflammatory agents (isoxicam type)

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13
Q

ifene (MSK)

A

antiestrogens of clomifene and tamoxifen groups

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14
Q

iximab (MSK)

A

monoclonal antibodies

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15
Q

methacin (MSK)

A

anti-inflammatory agents (indomethacin types)

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16
Q

nal (MSK)

A

narcotic agonists/antagonists (normorphine type)

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17
Q

nercept (MSK)

A

tumor necrosis factor receptors

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18
Q

profen (MSK)

A

anti-inflammatory/analgesic agents (ibuprofen type)

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19
Q

tacept (MSK)

A

T-cell receptors

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20
Q

trexate (MSK)

A

antimetabolites (folic acid derivatives)

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21
Q

triptan (MSK)

A

anti-migraine agents (5-HT1 receptor agonists) (sumatriptan derivatives)

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22
Q

xostat (MSK)

A

xanthine oxidase/dehydrogenase inhibitors

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23
Q

atadine (Resp)

A

tricyclic histamine-H1 receptor agonists; loratadine derivatives (formerly -tadine)

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24
Q

astine (Resp)

A

antihistaminics (histamine H1 receptor antagonists)

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25
Q

drine (Resp)

A

sympathomimetics

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26
Q

lizumab (Resp)

A

monoclonal antibodies

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27
Q

lukast (Resp)

A

leukotriene receptor antagonists

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28
Q

orphan (Resp)

A

narcotic antagonists/agonists (morphinan derivatives)

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29
Q

pred (Resp)

A

prednisone and prednisolone derivatives

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30
Q

terol (Resp)

A

bronchodilators (phenethylamine derivatives)

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31
Q

trop(ium) (Resp)

A

atropine derivative (quaternary ammonium salt)

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32
Q

amivir (Immune)

A

neuraminidase inhibitors

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33
Q

bendazole (Immune)

A

anthelmintics (tibendazole type)

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34
Q

cavir (Immune)

A

carbocyclic nucleosides

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35
Q

cef (Immune)

A

cephalosporins

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36
Q

cillin (Immune)

A

penicillins

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37
Q

citabine (Immune)

A

nucleoside antiviral/antineoplastic agents, cytarabine or azarabine derivatives

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38
Q

conazole (Immune)

A

systemic antifungals (miconazole type)

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39
Q

cycline (Immune)

A

antibiotics (tetracycline derivatives)

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40
Q

cyclovir (Immune)

A

intivirals (acyclovir type)

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41
Q

floxacin (Immune)

A

fluoroquinolone (not from Stem list)

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42
Q

kacin (Immune)

A

antibiotics obtained from Streptomyces kanamyceticus (related to kanamycin)

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43
Q

lizumab (Immune)

A

monoclonal antibodies

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44
Q

micin (Immune)

A

antibiotics (Micromonospora strains)

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45
Q

mycin (Immune)

A

antibiotics (Streptomyces strain)

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46
Q

navir (Immune)

A

HIV protease inhibitors (saquinavir type)

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47
Q

nidazole (Immune)

A

antiprotozoal substances (metronidazole type)

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48
Q

nifur (Immune)

A

5-nitrofuran derivatives

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49
Q

oxacin (Immune)

A

antibacterials (quinolone derivatives)

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50
Q

oxanide (Immune)

A

antiparasitics (salycylanilide derivatives)

51
Q

prim (Immune)

A

antibacterials (trimethoprim type)

52
Q

rifa (Immune)

A

antibiotics (rifamycin derivatives)

53
Q

sulfa (Immune)

A

antimicrobials (sulfonamides derivatives)

54
Q

tegravir (Immune)

A

integrase inhibitors

55
Q

thromycin (Immune)

A

macrolide (not on Stem List)

56
Q

vir (Immune)

A

antivirals

57
Q

virenz (Immune)

A

non-nucleoside reverse transcriptase inhibitors; benzoxazinone derivatives

58
Q

viroc (Immune)

A

CC chemokine receptor type 5 (CCR5) antagonists

59
Q

vudine (Immune)

A

antineoplastics; antivirals (zidovudine group) (exeption: edoxudine)

60
Q

zolid (Immune)

A

oxazolidinone antibacterials

61
Q

azepam (Neuro)

A

antianxiety agents (diazepam type)

62
Q

azolam (Neuro)

A

(WHO Stem) diazepam derivatives

63
Q

caine (Neuro)

A

local anesthetics

64
Q

clone (Neuro)

A

hypnotics/tranquilizers (zopiclone type)

65
Q

dopa (Neuro)

A

dopamine receptor agonists

66
Q

faxine (Neuro)

A

antianxiety, antidepressant inhibitor of norepinephrine and dopamine re-uptake

67
Q

gab (Neuro)

A

gabamimetics

68
Q

giline (Neuro)

A

Monoamine oxidase (MAO) Inhibitors, type B

69
Q

Melteon (Neuro)

A

selective melatonin receptor agonist

70
Q

oxetine (Neuro)

A

antidepressants (fluoxetine type)

71
Q

peridol (Neuro)

A

antipsychotics (haloperidol type)

72
Q

peridone (Neuro)

A

antipsychotics (risperidone type)

73
Q

pezil (Neuro)

A

acetacholinesterase inhibitors used in the treatment of Alzheimer’s disease

74
Q

pidem (Neuro)

A

hypnotics/sedatives (zolpidem type)

75
Q

pin(e) (Neuro)

A

tricyclic compounds

76
Q

tiapine (Neuro)

A

antipsychotics (dibenzothiazepine derivatives)

77
Q

toin (Neuro)

A

antiepileptics (hydantoin derivatives)

78
Q

traline (Neuro)

A

selective serotonin reuptake inhibitors (SSRI)

79
Q

triptyline (Neuro)

A

antidepressants (dibenzo[a,d] cycloheptane derivatives)

80
Q

nicline (Neuro)

A

nicotinic acetylcholine receptor partial agonists

81
Q

barb (Neuro)

A

barbituric acid derivatives

82
Q

spirone (Neuro)

A

anxiolytics (buspirone type)

83
Q

fetamine (Neuro)

A

amfetamine derivatives

84
Q

piprazole (Neuro)

A

(WHO Stem) psychotropics, phenylpiperazine derivatives (future use discouraged due to conflict with stem
-prazole)

85
Q

racetam (Neuro)

A

nootropic agents (learning, cognitive enhancers), piracetam type

86
Q

sidone (Neuro)

A

antipsychotic with binding activity on serotonin (5-HT2A) and dopamine (D2) receptors

87
Q

tropine (Neuro & Cardio)

A

atropine derivatives; subgroups tertiary amines (E.g. benztropine)

88
Q

mantine (Neuro)

A

antivirals/antiparkinsonians (adamantane derivatives)

89
Q

alol (Cardio)

A

combined alpha and beta blockers

90
Q

azosin (Cardio)

A

antihypertensives (prazosin type)

91
Q

dil (Cardio)

A

vasodilators (undefined group)

92
Q

dipine (Cardio)

A

phenylpyridine vasodilators (nifedipine type)

93
Q

drazaline (Cardio)

A

antihypertensives (hydrazine-phthalazines)

94
Q

farin (Cardio)

A

warfarin analogs

95
Q

fibrate (Cardio)

A

antihyperlipidemics (clofibrate type)

96
Q

gatran (Cardio)

A

thrombin inhibitors (argatroban type)

97
Q

grel (Cardio)

A

platelet aggregation inhibitors, primarily platelet P2Y12 receptor antagonists

98
Q

imibe (Cardio)

A

antihyperlipidemics; acyl CoA: cholesterol acyltransferase (ACAT) inhibitors

99
Q

iodarone (Cardio)

A

indicates high iodine content antiarrhythmic

100
Q

nitro (Cardio)

A

(WHO Stem) NO2 derivatives

101
Q

olol (Cardio)

A

beta-blockers (propranolol type)

102
Q

pamil (Cardio)

A

coronary vasodilators (verapamil type)

103
Q

parin (Cardio)

A

heparin derivatives and low molecular weight (or depolymerized) heparins

104
Q

pril (Cardio)

A

antihypertensives (ACE inhibitors)

105
Q

sartan (Cardio)

A

angiotensin II receptor antagonists

106
Q

semide (Cardio)

A

diuretics (furosemide type)

107
Q

thiazide (Cardio)

A

diuretics (thiazide derivatives)

108
Q

tiazem (Cardio)

A

calcium channel blockers (diltiazem type)

109
Q

vastatin (Cardio)

A

antihyperlipidemics (HMG-CoA inhibitors)

110
Q

xaban (Cardio)

A

antithrombotics, blood coagulation factor XA inhibitors

111
Q

afil (Endocrine/Misc)

A

phosphodiesterase type 5 (PDE5) inhibitors

112
Q

estr (Endocrine/Misc)

A

Estrogens

113
Q

fenacin (Endocrine/Misc)

A

muscarinic receptor antagonists

114
Q

formin (Endocrine/Misc)

A

hypoglycemics (phenformin type)

115
Q

gest (Endocrine/Misc)

A

progestins

116
Q

gli or gly (Endocrine/Misc)

A

antihyperglycemics

117
Q

glinide (Endocrine/Misc)

A

antidiabetic, sodium glucose co-transporter 2 (SGLT2) inhibitors, not phlorozin derivatives

118
Q

gliptin (Endocrine/Misc)

A

dipeptidyl aminopeptidase-IV inhibitors

119
Q

glitazone (Endocrine/Misc)

A

peroxisome proliferator activating receptor (PPAR) agonists (thiazolidene derivatives)

120
Q

glutide (Endocrine/Misc)

A

glucagon-like peptide (GLP) analogs

121
Q

ster (Endocrine/Misc)

A

steroids (androgens, anabolics)

122
Q

steride (Endocrine/Misc)

A

testosterone reductase inhibitors

123
Q

tide (Endocrine/Misc)

A

peptides

124
Q

uracil (Endocrine/Misc)

A

uracil derivatives used as thyroid antagonists and as antineoplastics