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C2C > Drug performas > Flashcards

Drug performas Flashcards

1
Q

Paracetamol drug name

A

acetaminophen/N-(4-hydroxyphenyl)ethanamide

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2
Q

Paracetamol trade names

A

Tylenol
Calpol
Panadol

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3
Q

Paracetamol indications

A

Mild pain

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4
Q

Paracetamol how does it work

A

Inhibits production of prostaglandins which cause pain and inflammation (mainly in the brain)

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5
Q

Paracetamol side effects

A 
Allergic reaction
Rash
Swelling
Flushing
Low bp
fast heartbeat
rare
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6
Q

Contraindications paracetamol

A 
Hypersensitivity
analgesic nephropathy
renal disease
hepatic impairment
alcohol abuse
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7
Q

Paracetamol interactions

A

Alcohol - mild sedation, liver damage
Anticoagulants - increases effect
anti-convulsants
some antibiotics (amlodipine)

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8
Q

Paracetamol elimination

A

Kidneys - urine

98% eliminated in 24 hrs

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9
Q

Paracetamol advice

A

relieves pain and fever
2x tablets every 4-6 hours
no more than 8 in 24 hours

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10
Q

Ibuprofen drug name

A

(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid

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11
Q

Ibuprofen trade name

A 
advil
motrin
medipren
nurofen
proposal
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12
Q

Ibuprofen indications

A

Mild pain

Fever

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13
Q

Ibuprofen how does it work

A

blocks prostaglandin to reduce pain and swelling

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14
Q

Ibuprofen side effects

A 
Vomiting
heart burn
bloating
gas
diarrhoea
constipation
dizziness
gi ulcer
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15
Q

Ibuprofen contraindications

A

asthma that is NSAID/aspirin sensitive
known hypersensitivity
active GI bleeding
peptic ulcer

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16
Q

Ibuprofen interactions

A 
NSAIDs
Aspirin
corticosteroids
antihypertensives
anticoagulants
diuretics
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17
Q

Ibuprofen excretion

A

urine

24 hours

18
Q

Ibuprofen advice

A

take with meal or snack

19
Q

Co-codamol trade names

A

panadeine
codibar
tylex

20
Q

Co-codamol uses

A

mild to severe pain
children over 12
short term relief

21
Q

Co-codamol how does it work

A

reduces production of prostaglandins in the brain and spinal cord
mild opioid -small amount converted to morphine

22
Q

Co-codamol side effects

A 
constipation
nausea
vomiting
dizziness
light headedness 
infection
addiction
23
Q

Co-codamol contraindictions

A

known hypersensitivity
conditions where morphine/opioids are contraindicated
0-18 undergone tonsillectomy
breastfeeding

24
Q

Co-codamol interactions

A 
alcohol
some antibiotics 
antihistamines
anaesthetics
anticholinergics (block acetyl choline)
25
Q

Co-codamol elimination

A

Absorbed from GI tract
metabolised in liver
excreted in urine as glucuronic acid

26
Q

Co-codamol advice

A

don’t take anything else
2x every 4-6 hours
no more than 8 in 24 hrs
do not drive until you know how it affects you

27
Q

Chlorphenamine actions

A

relieves sinus congestion, watery eyes, runny nose, itchy throat, sneezing, due to colds, allergies, hay fever

28
Q

Chlorphenamine tradenames

A

Puritan

Qdall AR

29
Q

Chlorphenamine how does it work

A

prevents actions of histamine

30
Q

Chlorphenamine side effects

A 
dizziness
drowsiness
dry mouth/nose/throat
blurred vision
restlessness
31
Q

Chlorphenamine contraindications

A

known hypersensitivity to antihistamines, lactose, magnesium
monoamine oxidase inhibitor in last 14 days

32
Q

Chlorphenamine interactions

A

alcohol
sedatives
opioids
neuroleptics

33
Q

Chlorphenamine elimintation

A

metabolised and excreted primarily in urine

34
Q

Chlorphenamine advice

A

eases allergic reactions

common side effects are sleepiness - may affect driving

35
Q

Gaviscon trade names

A

tums

maalox

36
Q

What is gaviscon made of

A

aluminum hydroxide and magnesium carbonate

37
Q

Gaviscon how does it work

A

neutralises stomach acid to treat heartburn and sour stomach by forming a protective raft on top of the stomach when it comes into contact with acid

38
Q

Gaviscon side effects

A

nausea, constipation, diarrhoea, headaches

39
Q

Gaviscon contraindictions

A 
calcium carbonate
sodium hyroxide 
magnesium
stomach or intestinal blockage
constipation
haemorrhoids
40
Q

Gaviscon interactions

A

phosphate supplements (often contain potassium)
calcium supplements
other aluminium and calcium antacids

41
Q

Gaviscon elimination

A

faeces - GI tract

C2C (4 decks)

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