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Drug names > Drug Names: CV > Flashcards

Drug Names: CV Flashcards

1
Q

Propanolol

A

Non-Selective Beta Blocker (Class II Antiarrhythmic)

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2
Q

Carveidilol

A

Non-selective Beta Blocker (Class II Antiarrhythmic). Also blocks Alpha 1 (relaxes smooth muscle…)

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3
Q

Sotalol

A

Non-selective BB (Class II anti-a)

But also acts as a Class III anti-a as it inhibits the influx of K+ during the Phase 3 repolarisation. Thus increases refractory perior in all cardiac tissues

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4
Q

Metoprolol

A

Cardio-selective BB (Class II anti-a)

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5
Q

Atenolol

A

Cardio-selective BB (Class II anti-a)

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6
Q

Bisoprolol

A

Cardio-selective BB (Class II anti-a)

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7
Q

Nebivolol

A

Cardio-selective BB (Class II anti-a)

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8
Q

Prazosin

A

a1 Antagonist (Post-synaptic terminal) (relax smooth muscle)

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9
Q

Methyldopa

A

A2 Agonist (Pre-synaptic terminal) (relax smooth muscle)

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10
Q

Clonidine

A

A2 Agonist (pre-synaptic terminal) (relax smooth muscle)

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11
Q

Monoxidine

A

A2 Agonist (Pre-synaptic terminal) (relax smooth muscle)

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12
Q

Nifedipine

A

Dihydropyridine CCB (Class IV anti-a)

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13
Q

Felodipine

A

Dihydropyridine CCB (Class IV anti-a)

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14
Q

Amlodopine

A

Dihydropyridine CCB (Class IV anti-a)

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15
Q

Diltiazem

A

Benzothiazepine CCH (Class IV anti-a)

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16
Q

Verapamil

A

Phenylalkylamina CCH (Class IV anti-a)

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17
Q

Glyceryl Trinitrate

A

Nitrate

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18
Q

Isosorbide mononitrate

A

Nitrate longer acting

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19
Q

Isosorbide Dinatrate

A

Nitrate longer acting

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20
Q

Nicorandil

A

Nitrate

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21
Q

Perhexiline

A

Nitrate

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22
Q

Enalapril

A

ACEI

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23
Q

Captopril

A

ACEI

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24
Q

Fosinopril

A

ACEI

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25
Q

Lisinopril

A

ACEI

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26
Q

Candesartan

A

ARBs

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27
Q

Irbesartan

A

ARBs

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28
Q

Losartan

A

ARBs

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29
Q

Mannitol

A

Osmotic Diuretics

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30
Q

Hydrochlorothiazide

A

Thiazide

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31
Q

Chlorthalidone

A

Thiazide

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32
Q

Bendofluazide

A

Thiazide

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33
Q

Indapamide

A

Thiazide

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34
Q

Frusemide

A

Loop Diuretic

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35
Q

Ethecrynic Acid

A

Loop Diuretic

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36
Q

Bumetanide

A

Loop Diuretic

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37
Q

Piretanide

A

Loop Diuretic

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38
Q

Spironolactone

A

K+ Sparing Diuretic

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39
Q

Amiloride

A

K+ Sparing Diuretic

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40
Q

Triamterene

A

K+ Sparing Diuretic

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41
Q

Allopurinol

A

Used for gout, which can be a side effect of diuretics

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42
Q

Quinidine

A

Class 1a Anti-a

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43
Q

Lignocaine

A

Class 1b Anti-a

44
Q

Mexiletine

A

Class 1b Anti-a

45
Q

Flecainide

A

Class 1c Anti-a

46
Q

Amiodarone

A

Class III Anti-a. Also has actions similar to Class IV(CCB), Class II (BB) and Class I(inhibits Na+ influx during phase 0). Amiodarone pulmonary fibrosis and thyroid problems

47
Q

Sotalol

A

Non-selective BB AND Class III Anti-a

48
Q

Digoxin

A

Class V Anti-a

49
Q

Atropine

A

Class V Anti-a AND Endogenous neurotransmitter used in shock

50
Q

Adenosine

A

Class V

51
Q

Adrenaline

A

Class V

52
Q

Isoprenaline

A

Class V

53
Q

Noradrenaline/Adrenaline

A

ENdogenous Neurotransmitters. Used in Shock

54
Q

Atropine

A

Endogenous Neurotransmitters. Used in Shock. AND Class V

55
Q

Dopamine

A

Endogenous Neurotransmitters. Used in Shock.

56
Q

Vasopressin

A

Endogenous Neurotransmitter. Used in Shock

57
Q

Dobutamine

A

Sympathomimmetic - used in shock

58
Q

Saline

A

Crystalloid Fluid replacement

59
Q

Albumex

A

Colloid Fluid Replacement

60
Q

Haematcel

A

Colloid Fluid Replacement

61
Q

Activated Protein C

A

Anticoagulation treatment in shock

62
Q

Gemfibrozil

A

TG-lowering drug

63
Q

Nicotinic Acid

A

TG-lowering drug

64
Q

Atorvastatin

A

LDL-lowering statin

65
Q

Simvastatin

A

LDL-lowering statin

66
Q

Pravastatin

A

LDL-lowering statin

67
Q

Fluvastatin

A

LDL-lowering statin

68
Q

Cholestyramine

A

Cholesterol Absorption Inhibitor

69
Q

Ezetimibe

A

Cholesterol Absorption Inhibitor

70
Q

Torcetrapid

A

HDL increasing drug?

71
Q

Low dose aspirin

A

Anti-platelet

72
Q

Clopidogrel

A

Anti-platelet

73
Q

Abciximab

A

Anti-platelet

74
Q

Streptokinase

A

Fibrinolytic/thrombolytic drug

75
Q

TPA, rTPA: Alteplase, Reteplase, Tenecteplase

A

Fibrinolytic/thrombolytic drugs

76
Q

Heparin

A

Anti coagulant

77
Q

LMWH

A

Anti-coagulant

78
Q

Warfarin

A

Anti coagulant

79
Q

Rivaroxaban

A

Anti coagulant

80
Q

Dabigatran

A

Anti coagulant

81
Q

Apixaban

A

Anti coagulant

82
Q

Vitamin K

A

Pro-coagulant

83
Q

codeine, pholcodeine, oxycodone, dihydocodeine, dextromethorphan

A

Anti-tussives for dry cough

84
Q

Guaifenesin, ammonium salts, senega, liquorice and sodium citrate

A

Anti-tussives: Expectorants

85
Q

Linctus

A

Anti-tussive: productive cough, demulcents

86
Q

Bromhexine, Acetylcysteine

A

Anti-tussives: Mucolytics

87
Q

Codeine, Paracetamol

A

Analgesics

88
Q

Prednisolone

A

Oral Glucocorticoid (anti-inflammatory, respiratory)

89
Q

Becolmethasone

A

Preventer: Inhaled glucocorticoids

90
Q

Budesonide

A

Preventer: Inhaled glucocorticoids

91
Q

Fluticasone

A

Preventer: Inhaled Glucocorticoids

92
Q

Salbutamol

A

Reliever: SABA (bronchidilator) (ventolin) (bronchodilation + decresed mucous production)

93
Q

Terbutaline

A

Reliever: SABA (bronchidilator) (Bricanyl) (bronchodilation + decreased mucous production)

94
Q

Salmeterol

A

Preventer: LABA (severent) (bronchodilation + decreased mucous production)

95
Q

Eformeterol

A

Preventer: LABA (Oxis) (bronchodilation + decreased mucous production)

96
Q

Ipratropium Bromide

A

Reliever (short acting): Muscarinic Antagonists (suppresses parasympathetic activity, leading to bronchidilation and decreased mucous production)

97
Q

Tiotropium Bromide

A

Symptom Controller (long acting): Muscarinic Antagonist (suppresses parasympathetic activity, leading to bronchodilation and decreased mucous production)

98
Q

Montelukast

A

Both preventer and reliever: Leukotriene receptor antagonist (anti-inflammatory)

99
Q

Zafirlukast

A

Both preventer and reliever: Leukotriene receptor antagonist (anti-inflammatory)

100
Q

Sodium cromoglycate

A

Both preventer and reliever: Chloride channel blocker. Stabilizes mast cells

101
Q

Nedocromil Sodium

A

Both preventer and reliever: chloride channel blocker. Stabilises mast cells.

102
Q

Theophylline

A

Both preventer and reliever: Xanthine bronchodilator (long acting bronchodilator used in persistent asthma, has to be used 4d)

103
Q

Aminophylline

A

Both preventer and reliever: Xanthine bronchidilator (long acting bronchodilator used in persistent asthma, has to be used 4d)

104
Q

Indomethacin, Naproxen, Aspirin, Ibuprofen, paracetamol, diclofenac

A

NSAIDS: non-steroidal anti-inflammatory drugs

105
Q

Celecoxib, Rofecoxib, Lumiracoxib

A

COX2 Inhibitors: Anti-inflammatory

106
Q

Action of Class I

A

Slow depolarisation (phase 0) by blocking fast Na+ channels. This slows depolarisation, thus slowing rate of contractions. Thus can help to prevent arrhythmias. Lognocaine has rapid dissociation time, and binds to both open and closed channels, thus it has the lowest pro-arrhythmic affect because by dissociating quickly, it effecitvely differentiates between normal and abnormal cardiac cells: normal cells will not be slowed by lignocaine, only abnormally behaving cells.

107
Q

What to BBs do?

A

Antagonise SNS activity by binding to B1 and B2 receptors. B1 antagonists - block NA/A from binding, causing cardiac muscle relaxation. B2 antagonists - block NA/A from binding, thus contract smooth muscle.
There are non-selectives and B1 selectives. All non selectives at high enough concentrations. Negative inotrope and neg chronotrope as mainly act by inhibiting Ca+ entry into the cell. Thus good for HTN, angina….

Drug names (1 decks)

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