Drug Names BPH/UI Flashcards

1
Q

Finasteride

A

Proscar
5-alpha-reductase Inhibitor
More Selective (Type 2)

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2
Q

Dutasteride

A

Avodart
5-alpha-reductase Inhibitor
Non-Selective (Type 1 & 2)

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3
Q

Alfuzosin

second gen

A

Uroxatral
Post-synaptic alpha1-adrenergic antagonist
Relax intrinsic urethral sphincter and prostatic smooth muscle

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4
Q

Doxazosin

second gen

A

Cardura
Post-synaptic alpha1-adrenergic antagonist
Relax intrinsic urethral sphincter and prostatic smooth muscle

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5
Q

Terazosin

second gen

A

Hytrin
Post-synaptic alpha1-adrenergic antagonist
Relax intrinsic urethral sphincter and prostatic smooth muscle

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6
Q

Prazosin

second gen

A

Minipress
Post-synaptic alpha1-adrenergic antagonist
Relax intrinsic urethral sphincter and prostatic smooth muscle

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7
Q

Silodosin

third gen

A

Rapaflo
Prostatic alpha1A adrenergic antagonist
VERY selective

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8
Q

Tamsulosin

third gen

A

Flomax
Prostatic alpha1A adrenergic antagonist
VERY selective

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9
Q

Darifenacin

A

Enablex
Anticholinergic
prevent detrusor muscle contractions
M3 selective

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10
Q

Oxybutynin IR, XL

A

Ditropan IR, Ditropan XL
Anticholinergic
prevent detrusor muscle contractions
Non-selective prodrug

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11
Q

Solifenacin

A

Vesicare
Anticholinergic
prevent detrusor muscle contractions
M3 selective

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12
Q

Tolterodine IR, LA

A
Detrol, Detrol LA
Anticholinergic
prevent detrusor muscle contractions
M3 selective
CYP2D6*5 = Poor Metab
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13
Q

Trospium IR, Trospium

A

Sanctura, Sanctura XR
Anticholinergic
prevent detrusor muscle contractions
Non-selective

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14
Q

Fesoterodine

A

Toviaz
Anticholinergic
prevent detrusor muscle contractions
M3 selective

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15
Q

Oxybutynin TDS (patch)

A
Oxytrol
Anticholinergic
(OTC)
prevent detrusor muscle contractions
Non-selective prodrug
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16
Q

Oxybutynin gel

A

Gelnique
Anticholinergic
prevent detrusor muscle contractions
Non-selective prodrug

17
Q

Imipramine

A

Tofranil (?)

Tri-Cyclic antidepressant

18
Q

Duloxetine

A

Cymbalta
SSNRI
(For UI) Approved in Europe; not in US