Drug Names Flashcards
Bethanechol Chloride
- Urinary Tract Stimulant
- Cholinergic
Furosemide
-Loop diuretic
Hydrochlorothiazide
- Thiazide diuretic
- Antihypertensive
HRT (Hormone replacement therapy) drugs
- Estrogen
- Progesterone
COC (combination oral contraceptives) drugs
- Estrogen
- Progesterone
Sildenafil
- Erectile dysfunction agent
- Vasodilator
Testosterone
Androgen (hormone)
Nitroglycerin
- Antianginal
- Nitrates
Garlic (raw, uncooked)
- Herbal supplement
- Lipid-lowering agent
Gingko (biloba)
- Supplement
- Antiplatelet
- CNS stimulant
Peak
Highest level of drug in blood stream
Trough
Lowest level of drug in blood stream
Therapeutic window
Range of drug in blood that falls between minimum effective concentration and toxic concentration
Half-life
The time required for amount of drug in body to decrease by 50%
Drug tolerance:
Opioid naive vs. opioid tolerant
How many pregnancy categories in relation to drugs?
A,B,C,D,X (4)
Pregnancy category A:
Human trials have shown no risk to fetal development
Pregnancy category B:
In animal trials, drug showed no negative effects to developing fetus
Pregnancy category C:
Show some risk to fetus; but benefits outweigh risks
Pregnancy category D:
Should only be used in life-threatening situations due to possible significant consequences to fetus and the pregnancy in general
Pregnancy category X:
Will terminate the pregnancy (abortion or deliver/induction)
First-pass effect
Liver metabolizes drug to such an extent that only a small amount of active drug emerges
Absorption
Movement of drug from set of administration into the blood
Enteral (via GI tract) is what type of administration?
Oral (PO)
Parenteral (outside of GI tract) is what type of administration?
- IV
- IM
- Sub Q
Distribution
Movement of drug to cite of action (ALBUMIN!)
Can all drug cross BBB?
NO
What drugs can cross BBB?
Lipid soluble or drugs that contain a transport system
Metabolism (“biotransformation”)
The enzymatic transformation of a drug structure (LIVER! most often)
Excretion
Removal of drug from body (URINE! usually)
Allergic reaction
Immune response (severe= resulting in systemic vasodilation, bronchoconstrictiion, and laryngeal edema)
Drug reactions
Know your drugs! and assess your patient!
Levodopa/Carbidopa
- Antiparkinsonian
- Dopamine agonist
Prednisone
- Corticodsteroids
- Immune modifiers
Vlaproic acid (depakote)
- Anticonvulsants
- Vascular headache suppressant
Levothyroxine
- Hormones
- Thyroid Preparation
Simvastatin
- Lipid lowering
- Statins
Insulin lispro
rapid-acting
insulin aspart
rapid-acting
insulin glulisine
rapid-acting
concentrated lisper U-200
rapid-acting
When should rapid acting insulin be given?
- immediately before meal
- at home: inject and eat