Drug Names

Question 1

Thiazide Diuretic (1)

Answer 1

Bendrofluazide - promotes Na+ / water excretion from the kidneys by inhibiting reabsorption in the loop of henle

Question 2

Loop Diuretic (1)

Answer 2

Furosemide

Question 3

Cardioselective Beta Blockers (2)

Answer 3

Atenolol, Bisoprolol - only block B1 adrenoceptors.

Question 4

Non - specific Beta Blocker (1)

Answer 4

Propranolol - decreases inotropy, lusitropy (relaxation rate), chronotropy, dronotropy
and causes mild vasoconstriction

Question 5

Dihydropyridine Calcium Channel Blocker (1)

Answer 5

Amlopidine - Acts on vascular smooth muscle, inhibiting the inwards movement of Ca2+

Question 6

Rate limiting Calcium Channel Blockers (2)

Answer 6

Verapamil, Diltiazem

Question 7

Direct Vasodilator - alpha 1 blockers (2)

Answer 7

Prazosin, Doxazosin

Question 8

Direct Vasodilator - ACE inhibitors (4)

Answer 8

Lisinopril, Ramipril, Catopril, Enalapril
Blocks the conversion of angiotensin 1 into angiotensin 2. Angiotensin 2 is a strong vasoconstrictor, and it promotes the production of aldosterone which increases Na+ and water retention

Question 9

Direct Vasodilator - Angiotensin Receptor Blockers (2)

Answer 9

Losartan, Valsartan

Question 10

Nitrates (2)

Answer 10

Isosorbide Mononitrate, Glyceryltrinitrate (normally spray)

Question 11

Potassium Channel opener (1)

Answer 11

Nicorandil

Question 12

Ivabridine

Answer 12

Ivabridine - Specifically inhibits the If current, prolonging diastolic time

Question 13

Antiplatelet - Inhibits TXA2 (1)

Answer 13

Aspirin

Question 14

Antiplatelet - Inhibits ADP (3)

Answer 14

Clopidogrel, Prasugrel, Ticagrelor

Question 15

Antiplatelet - Inhibits Thrombin (2)

Answer 15

Heparin (weak), Bivalrubin

Question 16

Antiplatelet - Inhibits Glycoprotein IIa/IIb receptors (3)

Answer 16

Tirofiban, Eptifibatide, Abciximab

Question 17

Anticoagulants (7)

Answer 17

Wharfarin, Heparin, Rivaroxiban, Fondaparinux, Apixaban, Edoxaban (Xa), Dabigatran (IIa)

Question 18

Fibrinolytic (3)

Answer 18

Streptokinase (++ effect with aspirin), Alteplase, Duteplase

Question 19

Statins (2)

Answer 19

Simvastatin, Atorvastatin

Question 20

Fibrates (2)

Answer 20

Bezafibrate, Gemfibrozil

Question 21

Bile acid binding resins (3)

Answer 21

Colestyramine, Colestipol, Colsevelam

Question 22

Ezetimbe (1)

Answer 22

Ezetimbe

Question 23

Anti - Arrhythmic Class 1 (3)

Answer 23

1A - Disopyramide. Moderate rate of dissociation. Prolonged refractory period, slow rise of AP
1B - Lignocaine. Fast rate of dissociation. Prevents premature beats
Ic - Flecainide. Slow rate of dissociation. Depressed conduction

Question 24

Anti - Arrhythmic Class 2 (1)

Answer 24

Metaprolol - B-adrenoceptor antagonist decreases the rate of depolarisation in SA and AV nodes

Question 25

Anti - Arrhythmic Class 3 (1)

Answer 25

Amiodarone - K+ channel blocker. Prolongs AP duration, increases refractory period

Question 26

Anti - Arrhythmic Class 4 (1)

Answer 26

Verapamil - Ca2+ channel blocker (rate limiting), decreases the force of cardiac contraction

Question 27

Digoxin (1)

Answer 27

Digoxin 1 - Blocks A-V conduction - produces an AV conduction delay. Blocks the SARCOLEMMA ATPase, K+/Na+ ATPase blocked, increases the contractility of the heart

Question 28

Calcium sensitisers (1)

Answer 28

Levosimedan - binds to troponin C in cardiac muscle, sensitising it to Ca2+. Also opens K+ channels in vascular smooth muscle causing vasodilation

Question 29

Beta - Adrenoceptor Agonists (2)

Answer 29

Adrenaline (alpha/beta agonist), Dobutamine (Beta - selective) (IV)

Question 30

Non - selective Muscarinic Ach Receptor Antagonist (1)

Answer 30

Atropine - Use >600mg. Increases HR in normal subjects. Used for managing severe bradycardia