Drug monitoring Flashcards
statins
LFT baseline, 3 and 12 months
ace in
U&E- prior, increases dose, annually
Amiodarone
TFT, LFT, U&E, CXR prior
TFT LFT 6 months
Methotrexate
FBC, LFT, U&E- prior and weekly until established. then 2-3monthly.
azathioprine
FBC LFT- prior, weekly for 4 weeks (FBC only), then 3 monthsly.
Lithium- regular monitoring
TFT U&E- prior
Lithium level weekly until stable then 3 monthly
TFT and U&E 6 months
Sodium valporate
LFT FBC before.
LFT periodically during 6 months
Glitazones
LFT before and regularly during.
Lithium range
0.4-1mmol/l
take 12 hours post-dose
Ciclosporin
trough levels immediately before dose
digoxin
6hrs post-dose
Phenytoin
trough levels before dose if- adjusting dose, suspecting toxicity, detection of non-adherence.