Drug Monitoring

Question 1

TFT monitoring on levothyroxine

Answer 1

3 monthly until 2 stable results (close together and normal range) then annually

Question 2

Amiodarone before treatment
and ongoing

Answer 2

CXR, ECG, U&E, LFT, TFT before treatment

TFT 6 monthly

Question 3

Clozapine FBC monitoring

Answer 3

Every week for 18 weeks
Then every 2 weeks up to 1 year
Then monthly after 1 year

Question 4

ACEI monitoring

Answer 4

U&E before starting and increasing dose, also 1-2 weeks after starting

Question 5

Monitoring benefit of furesemide

Answer 5

Daily weights

Question 6

Atorvastatin monitoring

Answer 6

Cholesterol, LFT, U&E, TFT before starting
LFTs 3 months and 12 months
CK in patients before starting with unexplained muscule pain

Question 7

When to stop statins

Answer 7

LFT 3x upper normal reference range

Question 8

ACEI electrolyte disturbance

Answer 8

Hyperkalaemia and AKI

Question 9

Hba1c target concentration

Answer 9

48 mmol/L

Question 10

Oxygen monitoring

Answer 10

Arterial blood gases (hypercapnic respiratory failure)

Question 11

Rivaroxaban

Answer 11

Patient reported symptoms of anaemia

Question 12

COCP

Answer 12

Weight and BP

Question 13

IV aminophylline

Answer 13

4-6 hours after treatment

Question 14

Oral aminophylline

Answer 14

5 days after treatment then 3 days after dose change

Question 15

Lithium patient parameters

Answer 15

U&E, TFT, FBC, BMI, ECG (if risk factors) before treatment

U&E, TFT, BMI every 6 months

Question 16

Lithium level monitoring

Answer 16

12 hours after dose aim for 0.4-1mmol/L (0.8-1 in acute mania)

Monitoring weekly after dose change until stable

Then 3 monthly for first year

Then 6 monthly (if narrower target range remain 3 monthly)

Question 17

Methotrexate monitoring

Answer 17

FBC, U&E, LFT every 1-2 weeks until stable

Then every 2-3 months

Question 18

Sodium valproate

Answer 18

FBC and LFT before therapy

LFT 6 monthly

Question 19

Fluid bolus

Answer 19

HR and BP

Question 20

Response after antibiotics

Answer 20

CRP after few days

Question 21

Enoxaparan

Answer 21

Platalets before initiation and after 4 days