Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacotherapy 3 > Drug MOA > Flashcards

Drug MOA Flashcards

1
Q

Sulfonylureas

A

Stimulate insulin release form pancreatic beta cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Meglitinides

A

Stimulate insulin release from pancreatic beta cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Metformin 2,000mg

A

Decreases hepatic glucose production

Increases insulin sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

TZDs

A

PPAR gamma agonist
-activation of PPAR gamma regulates the transcription of genes involved in glucose and lipid metabolism
Increases insulin sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

GLP-1 agonists

A

Binds to and stimulates pancreatic GLP-1 receptor

- enhances glucose dependent insulin secretion
- suppresses inappropriately elevated glucagon
- slows gastric emptying
- improves satiety
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

DPP-4 inhibitors

A

Inhibits DPP-4 enzyme, thereby slowing inactivation of endogenous GLP-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SGLT-2 inhibitors

A

Inhibits glucose reabsorption in the kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Amylinomimetic

A 
Amylin agonist
Decreases hepatic glucose production after meals
Decreases post-prandial rise in glucagon
Delays gastric emptying
Improves satiety
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Alpha Glucosidase inhibitors

A

Competitive inhibition of glucosidases in small intestine

Decrease absorption of carbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Colesevelam

A

Bile acid sequestrant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Glipizide 5mg

A

Sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Glyburide 5mg

A

Sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Glimepiride 1-2mg

A

Sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Repaglinide

A

Meglitinide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Nateglinide

A

Meglitinide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rosiglitazone

A

TZD

17
Q

Pioglitazone 15-30mg

A

TZD

18
Q

Exenatide BID

Exenatide XR QW

A

GLP-1 agonist

19
Q

Liraglutide QD

A

GLP-1 agonist

20
Q

Albiglutide QW

A

GLP-1 agonist

21
Q

DulaglutideQW

A

GLP-1 agonist

22
Q

Linagliptin

A

DPP-4 inhibitor

23
Q

Alogliptin

A

DPP-4 inhibitor

24
Q

Sitagliptin

A

DPP-4 inhibitor

25
Q

Saxagliptin

A

DPP-4 inhibitor

26
Q

Canagliflozin

A

SGLT-2 inhibitor

27
Q

Dapagliflozin

A

SGLT-2 inhibitor

28
Q

Empagliflozin

A

SGLT-2 inhibitor

Pharmacotherapy 3 (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions