Drug MOA Flashcards
Calcium Carbonate (TUMS)
neutralize gastric acid and increases gastric pH
Magnium hydroxide (Milk of Magnesia)
neutralize gastric acid and increases gastric pH (GERD)
Osmotic with ions that draws fluid into stool to induce peristalsis (Constipation)
Mylanta Supreme
neutralize gastric acid and increases gastric pH
Famotidine (Pepcid)
reversibly binds inhibits H2 receptors to decrease gastric acid secretions
Ranitidine
reversibly binds inhibits H2 receptors to decrease gastric acid secretions
Cimetidine
reversibly binds inhibits H2 receptors to decrease gastric acid secretions
Remember: gynecomastia and impotence
Esomeprazole (Nexium)
irreversibly binds to H+/K+ ATPase on parietal cells to block gastric acid secretion
Lansoprazole (Prevacid)
irreversibly binds to H+/K+ ATPase on parietal cells to block gastric acid secretion
Omeprazole (Prilosec)
irreversibly binds to H+/K+ ATPase on parietal cells to block gastric acid secretion
Pantoprazole (Protonix)
irreversibly binds to H+/K+ ATPase on parietal cells to block gastric acid secretion
Dexlansoprazole (Dexilant)
irreversibly binds to H+/K+ ATPase on parietal cells to block gastric acid secretion
Metoclopramide (Reglan)
Dopamine antagonist that blcks serotonin receptors to decrease nausea and vomiting. Enhances response of ACh in upper GI tract to accelerate gastric emptying and increase LES tone/pressure
Misoprostol
prostaglandin E1 analog that mimics PG to have gastro-protectice abilities
Sucralfate (Carafate)
a sucrose-sulfate-aluminum complex that forms a protective barrier around the open ulcer
Psyllium (Metamucil)
Bulk forming anti-constipation drug that absorbs water to add bulk into the stool to increase peristalsis