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AML: Behavioral Health EOR > Drug MOA > Flashcards

Drug MOA Flashcards

1
Q

Inhibits enzyme aldehyde dehydrogenase, increases acetaldehyde.

A

Disulfiram

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2
Q

Block reuptake of 5-HT (Serotonin) and NE.

A

SNRI

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3
Q

Selective NE reuptake inhibitor. Not controlled.

A

Atomoxetine

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4
Q
A
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5
Q

Selectively inhibits 5-HT reuptake. No M, H1, or A1 blockade.

A

SSRI

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6
Q

Histamine (H1) receptor agonist.

A

Hydroxyzine

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7
Q

Stimulates alpha-2 adrenergic receptors.

A

XR Clonidine, XR Guanfacine

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8
Q

Na+ channel blocker. Inhibits glutamate.

A

Lamotrigine

[Anticonvulsant]

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9
Q

Opens chloride channels. Inhibits GABA.

A

Valproic Acid/Valproate

[Anticonvulsant]

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10
Q

Partial opioid agonist.

A

Buprenorphine

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11
Q

Partial agonist of nicotinic receptor. Decreases withdrawal and interferes w/ reward.

A

Varenicline (Chantix)

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12
Q

L.A. opioid agonist.

A

Methadone

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13
Q

Blocks Dopamine release, antagonizes Mu receptor, decreases craving and reward. Opioid antagonist– completely blocks effects.

A

Naltrexone

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14
Q

Enhance GABA at receptor.

A

Benzodiazepines

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15
Q

Partial agonist 5-HT.

A

Vilazadone/Vortioxetine

[Serotonin Modulators or Serotonin Partial Agonist/Reuptake Inhibitor (SPARI)]

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16
Q

Blocks Dopamine and NE reuptake. Antagonizes nicotinic receptor.

NE/Dopamine Reuptake Inhibitor (NDRI)

17
Q

Break down Serotonin and NE and Dopamine. Increases amt. of 5-HT, NE, and DA.

A

MAOI (Monoamine Oxidase Inhibitors)

18
Q

Blocks catecholamine reuptake. NE, Dopamine; increases intrasynaptic levels.

A

Methylphenidate

19
Q

Blocks catecholamine reuptake. NE, Dopamine; increases intrasynaptic levels. Increases Dopamine release.

A

Amphetamines

20
Q

Inhibits kindling and repetitive firing of APs by inactivating Na+ channels.

A

Carbamazepine

[Anticonvulsant]

21
Q

Inhibits adenylate cyclase enzyme.

A

Lithium

[Mood Stabilizer]

22
Q

Dopamine and NE reuptake inhibitor. No blockade of cholinergic, histaminergic, and alpha-1 adrendergic receptors.

A

Bupropion

[Atypical Antidepressant]

23
Q

Restores glutamate. Stops withdrawal S/S.

A

Acamprosate

24
Q

S.A. opioid antagonist.

25
Q

5HT-1a receptor agonist. Dopamine receptors.

26
Q

Antagonize 5-HT.

A

Nefazadone/Trazodone

[Serotonin Modulators or Serotonin Antagonist/Reuptake Inhibitors (SARIs)]

27
Q

Inhibits reuptake of 5-HT and NE.

A

TCA (Tricyclic Antidepressants)

28
Q

Antagonizes alpha-2 and 5-HT-2 / 5-HT-3. Blocks presynaptic alpha-2 autoreceptors and heteroreceptors (= increases in NE and 5-HT, like SSRI). Potent 5-HT-2 and 5-HT-3 receptor blockade. Blocks muscarinic cholinergic, histamine-1, and alpha-1 adrenergic receptors.

A

Mirtazapine

[Atypical Antidepressant]

AML: Behavioral Health EOR (1 decks)

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