Drug List from Dr. Papke's Presentations

Question 1

What are the Benzodiazepines? (7) Which ones are short, intermediate, fast acting?

Answer 1

(1) Diazepam- long acting
(2) Flurazepam-
(3) Midazolam- short acting, IV only
(4) Triazolam- short acting
(5) Alprazolam- short to intermediate acting
(6) Lorazepam- short to intermediate acting
(7) Oxazepam-

Question 2

What is the Benzodiazepine antagonist? Is it short, intermediate, fast acting?

Answer 2

(1) Flumazenil- short acting, IV only

Question 3

What are the Barbituate drugs? (3) What are they primarily used for?

Answer 3

(1) Thiopental- ultra short acting due to increased lipid solubility
(2) Pentobarbital- primary used as anti-epileptic drug
(3) Phenobarbital- hypnotic with high abuse potential whose use has been largely displaced by safer benzodiazepines

Question 4

What is the drug that acts at the benzodiazepine binding site, but has unique structures therefore is not considered a Benzodiazepine? What is it used for?

Answer 4

Zolipidem; it is used as a sleep aid

Question 5

What is another sedative/hypnotic that is converted to trichloroethanol?

Answer 5

Chloral hydrate

Question 6

What are the Antihistamine drugs that are used as anxiolytics? (2)

Answer 6

(1) Hydroxzine

(2) Diphenhydramine

Question 7

What are the non-sedative anxiolytic drugs? (4)

Answer 7

(1) Buspirone
(2) Clonidine
(3) Propranolol
(4) Tricyclic Antidepressants

Question 8

What are the two drugs that are used for aversive therapy in alcoholism?

Answer 8

(1) Disulfiram

(2) Naltrexone

Question 9

What is the type of alcohol that is in most drinks?

Answer 9

Ethanol

Question 10

What are the 2 misguided Ethanol substitutes? Why are these bad?

Answer 10

Methanol, Ethylene Glycol; they have very toxic breakdown products (e.g. formaldehyde, formic acid)

Question 11

What are the Opioid drugs of abuse? (4)

Answer 11

(1) Heroin
(2) Morphine
(3) Methadone
(4) Codeine

Question 12

What are the Sympathomimetic drugs of abuse? (4)

Answer 12

(1) Amphetamines
(2) Methamphetamines
(3) Cocaine
(4) Caffeine

Question 13

What is the Cannabinoid drug of abuse? (1)

Answer 13

(1) THC

Question 14

What are the Inhalant drugs of abuse? (2)

Answer 14

(1) Nitrous oxide
(2) Amyl nitrite
(3) Butyl nitrite

Question 15

What is the designer drug of abuse? (1)

Answer 15

MDMA (ecstasy)

Question 16

What are the Psychedelic drugs of abuse? (4)

Answer 16

(1) LSD
(2) Mescaline
(3) PCP
(4) Ketamine

Question 17

What is the drug of abuse commonly found with smokers?

Answer 17

Nicotine

Question 18

What drug is used to treat opioid toxicity?

Answer 18

Naloxone

Question 19

What drug is used to as a substitution therapy for nicotine?

Answer 19

Varenicline

Question 20

What are the Tricyclic antidepressants? (2)

Answer 20

(1) Imipramine

(2) Amitryptiline

Question 21

What are the Heterocyclic antidepressants? (3)

Answer 21

(1) Mirtazapine
(2) Bupropion
(3) Venlafaxine

Question 22

What are the SSRIs (antidepressants)? (3)

Answer 22

(1) Fluoxetine
(2) Paroxetine
(3) Sertraline

Question 23

What are the MAO inhibitors (antidepressants)? (1)

Answer 23

(1) Phenelzine

Question 24

What are the mood stabilizers? (3)

Answer 24

(1) Lithium
(2) Divalproex
(3) Carbamazepine

Question 25

What anticonvulsants are sodium channel blockers? (3)

Answer 25

(1) Phenytoin (2) Carbamazepine (3) Lamotrigine

Question 26

What anticonvulsants enhance GABA neurotransmission? (5)

Answer 26

(1) Phenobarbital (2) Benzodiazepines (3) Valproic acid (4) Tiagabine (5) Gabapentin

Question 27

What anticonvulsants are calcium channel blockers? (3)

Answer 27

(1) Valproic acid (2) Ethosuximide (3) Lamotrigine

Question 28

What anticonvulsants decrease glutamate neurotransmission? (3)

Answer 28

(1) Valproic acid (2) Topiramate (3) Lamotrigine