Drug Interactions

Question 1

Statins + Grapefruit = ?

Answer 1

Muscle pains and aches

Question 2

Antiplatelets + NSAIDS = ?

Answer 2

Increased risk of bleeding

Question 3

Multivalent ions (Fe or Calcium) + Levothyroxine, Fluoroquinolones, Biphosphates or Tetracyclines = ?

Answer 3

Reduce effectiveness of drugs

Question 4

Nitrates + PDE5 (sildenafil) = ?

Answer 4

Severe Hypotension (low blood pressure)

Question 5

ACE inhibitors + Potassium elevating = ?

Answer 5

Risk of hyperkalemia (increased potassium)

Question 6

Ritonavir + Protease inhibitors = ?

Answer 6

Less dose of protease inhibitors

Question 7

Beta Blockers + Calcium Channel blocks = ?

Answer 7

Risk of heart failure

Question 8

Broad spectrum antibiotics + warfarin = ?

Answer 8

Increased risk of bleeding

Question 9

Digoxin + diuretics = ?

Answer 9

Digoxin toxicity (low potassium)

Question 10

Aminoglycosides + Loop diuretics = ?

Answer 10

ototoxicity and kidney damage

Question 11

Antihistamines + Benzodiazepines, SSRIs, antipsychotic drugs = ?

Answer 11

Sedation

Question 12

Macrolides, amiodarones, SSRIs, Fluroquinolones, Quinine, Antipsychotic, drugs can cause?

Answer 12

Pro long QT, heart rhythm problems

Question 13

Corticosteroids + NSAIDs = ?

Answer 13

peptic ulceration and GI bleeding

Question 14

MAO inhibitors + Tyramine = ?

Answer 14

hypertensive crisis

Question 15

Omeprazole + Clopidogrel = ?

Answer 15

reduce antiplatelet effect

Question 16

Macrolides + statins = ?

Answer 16

increase statin effect

Question 17

Sulfonylureas, metformin, thiazolidinediones = ?

Answer 17

hypoglycemia (lower blood glucose levels)

Question 18

Phenytoin + warfarin, estrogens, progestogens = ?

Answer 18

reduces concentrations of second 3

Question 19

Corticosteroids + beta 2 agonist = ?

Answer 19

hypokalemia (low potassium levels)

Question 20

Alpha blockers + antihypertensive = ?

Answer 20

Dangerously low blood pressure