drug induced liver injury Flashcards
pre hepatic is what kind of bilirubin
unconjigated
hepatic jaundices is what kind of bilirubin
both unconjugated and conjugatedconjicated
Post hepatic is which kind of bilirubin
conjigated
what conditions are associated with too much conjugated bilirubin
post hepatic jaundices = bile duct obstriction
- gallstones
-cholangiocarcinoma, strictures, or drug-induced cholestasis
-pancreatic cancer or abdominal masses (e.g. lymphomas)
what conditions are associated with too much unconjigated bilirubin
-gilberts
-Criggler-Najjar syndrome
-haemlytic anemia
what conditions are associted with mixed unconjigated and conjugated bilirubin
-alchohlic liver disesaes
-viral hepatitis
patient has pale stool what could this indicate
heptic/post hepatic jaundiced
patient has dark urine what could this be
heptic/post hepatic jaundiced
where is cholecystitis present
gallbaldder
where is cholengitis present
bile ducts
how do you manage gall stones in gallbladder
laprascopic cholectectomy
bile acid dissolution therapy
what is the management of gall stones in the bile ducts
ERCP
sugary for large stone
in gallstones do ultrasounds always show dilated ducts
no
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what are the most common drugs to cause drug induced liver injury
antibiotics (40%)
