Drug indications/comments Flashcards

1
Q

Rosuvastatin (Crestor) indication

A

Hyperlipidemia (IIa/IIb, IV)

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2
Q

Fluvastatin (Lescol/XL) indication

A

Hyperlipidemia (IIa/IIb)

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3
Q

Fluvastatin (Lescol XL) notes

A

Take at bedtime

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4
Q

Atorvastatin indication

A

Hyperlipidemia (IIa/IIb, IV)

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5
Q

Atorvastatin notes

A

Can be given at any time of day

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6
Q

Lovastatin (Mevacor) Indication

A

Hyperlipidemia IIa/IIb

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7
Q

Lovastatin (Mevacor) notes

A

Take with evening meal

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8
Q

Pravastatin (Pravachol) indication

A

Hyperlipidemia IIa/IIb

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9
Q

Pravastatin notes

A

Take at bedtime

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10
Q

Simvastatin (Zocor) indication

A

Hyperlipidemia IIa/IIb, IV

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11
Q

Simvastatin notes

A

Take in the evening; do not start 80mg due to myopathy risk

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12
Q

Gemfibrozil (Lopid)

A

Hyperlipidemia type IV

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13
Q

Gemfibrozil (Lopid) notes

A

Take 30 minutes before morning & evening meals

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14
Q

Fenofibrate (Tricor)

A

Hyperlipidemia Type IIa/IIb, IV

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15
Q

Fenofibrate (Tricor)

A

Take with food

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16
Q

Lovaza indication

A

HyperTG (>/= 500 mg/dL)

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17
Q

Lovaza notes

A

Take with food

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18
Q

Questran indication

A

Hyperlipidemia Type (IIa)

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19
Q

Questran notes

A

Can divide prn
max dose 24 grams
mix with water prior to administration

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20
Q

Colesevelam (Welchol) indication

A

Hyperlipidemia Type IIa

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21
Q

Colesevelam (Welchol) notes

A

Take with meals

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22
Q

Niacin (Niaspan) Indication

A

Hyperlipidemia Type (IIa/IIb, IV)

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23
Q

Niacin notes

A

Titration necessary

premedicate with ASA or NSAID

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24
Q

Ezetimibe (Zetia) indication

A

Hyperlipidemia Type IIa

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25
Q

Ezetimibe/simvastatin indication

A

Hyperlipidemia

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26
Q

Furosemide (Lasix) indication

A

CHF

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27
Q

Furosemide (Lasix) notes

A

May require BID dosing

oral dose >/= 300mg/day may be needed

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28
Q

Bumetanide (Bumex) indication

A

CHF

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29
Q

Bumetanide (Bumex) notes

A

Max dose of 10mg/day may be needed

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30
Q

Torsemide (Demadex) indication

A

CHF, HTN

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31
Q

Hydrochlorothiazide indication

A

HTN

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32
Q

Indapamide (Lozol) indication

A

CHF, HTN

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33
Q

Metolazone (Zaroxolyn) indication

A

CHF, renal dysfunction

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34
Q

Spironolactone (Aldactone) indication

A

Edema (CHF, cirrhosis), HTN

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35
Q

Spironolactone (Aldactone) notes

A

for HTN: can start 25mg QD, BID dosing is acceptable

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36
Q

Eplerenone (Inspra) indication

A

HTN

37
Q

Eplerenone (Inspra) notes

A

Titrate to 50mg BID after 4 weeks prn

38
Q

Dyazide indication

A

HTN

39
Q

Dyazide notes

A

37.5/25mg capsule

40
Q

Maxzide indication

A

HTN

41
Q

Maxzide notes

A

2 strengths: 37.5/25mg tabs, 75/50mg tabs

42
Q

Potassium chloride indication

A

supplement

43
Q

potassium chloride notes

A

Can divide to minimize GI upset

take with meals and full glass of water

44
Q

Clopidogrel (Plavix) indication

A

decreases risk of vascular events

45
Q

Ticlodipine (Ticlid) indication

A

Stroke reduction

46
Q

Clopidogrel (Plavix) notes

A

Report unusual bleeding

47
Q

Ticlodipine notes

A

Take with meals

48
Q

dipyridamole (Persantine) indication

A

thrombolic event risk reduction with warfarin (cardiac valve replacement)

49
Q

dipyridamole (Persantine) notes

A

Often co-administered with warfarin/ASA

50
Q

Aggrenox indication

A

CVA prevention with h/o TIA or CVA

51
Q

Aggrenox notes

A

strength: 200/25mg caps

52
Q

Pentoxifylline (Trental) indication

A

Intermittant claudication

53
Q

Pentoxifylline (Trental) notes

A

Take with meals

54
Q

Cilostazol (Pletal) indication

A

intermittant claudication

55
Q

Cilostazol (Pletal) notes

A

Take at least 30 minutes before or 2 hours after meals

56
Q

Warfarin (Coumadin) indication

A

A.Fib, VTE

57
Q

Warfarin (Coumadin) notes

A

Average dose 4-5mg/day; avoid alcohol & ASA

58
Q

Dabigatran (Pradaxa) indication

A

A.Fib

59
Q

Dabigatran (Pradaxa) notes

A

Seeking indication for VTE

60
Q

Terazosin (Hytrin) indication

A

HTN

61
Q

Terazosin (Hytrin) notes

A

Start at low dose, take 1st dose at bedtime

62
Q

Doxazosin (Cardura/XL) indication

A

XL: BPH
IR: HTN/BPH

63
Q

Cardura XL notes

A

Can increase to 8mg/day in 4 weeks

Take in AM with breakfast

64
Q

Cardura notes

A

Start at low dose

take 1st dose at bedtime to avoid syncope

65
Q

Prazosin (minipress) indication

A

HTN

66
Q

Prazosin (Minipress) notes

A

Start at low dose

Take 1st dose at bedtime to avoid syncope

67
Q

Hydralazine (Apresoline) indication

A

HTN

68
Q

Clonidine (Catepres) indication

A

HTN

69
Q

Clonidine notes

A

Do not skip doses (rebound HTN)

TTS: rotate application site

70
Q

Nifedipine (Procardia XL) indication

A

HTN, Vasospastic/CSA

71
Q

Nifedipine (Procardia XL) notes

A

Take on empty stomach

72
Q

Nifedipine (Procardia) indication

A

vasospastic/CSA

73
Q

Nifedipine notes

A

Not an optimal dosage form for this indication (Vasospastic/CSA)

74
Q

Felodipine (Plendil) Indication

A

HTN

75
Q

Amlodipine (Norvasc) indication

A

HTN, Vasospastic/CSA

76
Q

Lotrel indication

A

HTN

77
Q

Lotrel notes - strengths

A

2.5/10, 5/10
5/20, 10/20
5/40, 10/40

78
Q

Diltiazem (Cardizem/CD/XR) indication

A

CD/XR: HTN

IR: Angina prophylaxis

79
Q

Diltiazem notes

A

CD: take on empty stomach
IR: Take before meals and at bedtime

80
Q

Verapamil (Isoptin/SR) indication

A

SR: HTN
IR: Vasospastic/CSA

81
Q

Verapamil notes

A

SR: 120-480mg/day
IR: Usual daily dosage range 240-480 mg/day

82
Q

Isosorbide dinitrate/SR indication

A

Angina prophylaxis

83
Q

Isosorbide dinitrate/SR notes

A

IR: dose at 7-12-5 for nitrate free interval
SR: dose at 8 and 2 for nitrate free interval

84
Q

Isosorbide mononitrate indication

A

angina prophylaxis

85
Q

Nitrostat indication/notes

A

acute anginal pain; PRN

86
Q

Nitro-Dur indication/notes

A

prevention and treatment of angina; do not wear for >12 hours unless directed

87
Q

Digoxin (Lanoxin) indication

A

CHF/A.Fib and flutter

88
Q

Amiodarone (Cordarone) indication/notes

A

Atrial and Ventricular arrhythmias; multiple drug interactions

89
Q

Dronedarone (Multaq) indication/notes

A

A.Fib and flutter; take with meals