Drug Examples Flashcards
Gabapentin
Used in the treatment of epilepsy
Blocks presynaptic Ca2+ channels - decreasing release of glutamate - decreases excitation
Carbamazepine
Used in treatment of epilepsy - decreases excitation
Blocks postsynaptic Na+ channels - preventing AP generation
What are Benzodiazepines & Barbiturates examples of?
CNS depressants
Ketamine & PCP are…
Dissociative anaesthetics
Opium, heroin, fentanyl & oxyContin are…
Narcotic analgesics
LSD, mescaline, DMT, psilocybin, MDMA are…
Hallucinogens
Nitrous oxide, amyl nitrite, lighter gas & household aerosols are…
Inhalants
Cocaine, amphetamine, nicotine, MDMA are…
CNS stimulants
3 examples of NDC neuromuscular blockers
Tubocurarine
Pancuronium
Gallamine
Alcuronium
Atracurium
Vecuronium
2 examples of DNC neuromuscular blockers
Suxamethonium
Decamethonium
Suxamethonium
DNC neuromuscular blocker
Used in intubation
Scoline apnoea - individuals with mutant esterases which cannot metabolise suxamethonium
EDTA (chelating agent)
Used in treating lead poisoning - binds to lead and forms a less toxic chelate
Example of chemical antagonism
Salbutamol
Used in the treatment of asthma
Artificial adrenoceptor agonist - activates adrenoceptors in the lungs, causes the relaxation of bronchial smooth muscle
Targets b2 adrenoceptors found in the lungs rather than b1 adrenoceptors found in the heart - so the heart doesn’t race
Sulfonamides & sulfones
Antimalarial drugs which inhibit dihydropteroate synthase
Proguanil & pyrimethamine
Anti-malarial drugs which inhibit dihydrofolate reductase