Drug Discovery Flashcards
1
Q
ASO
A
Antisense Oligonucleotide
2
Q
DMT
A
Disease Modifying Therapy
3
Q
MTC
A
Maximum Tolerated Concentration
4
Q
MEC
A
Minimum Effective Concentration
5
Q
PK/PD
A
Pharmacokinetics / Pharmacodynamics
6
Q
Main 2 causes of failure for drugs between preclinical and market.
A
Lack of efficacy & Lack of safety
7
Q
Target
A
Cellular or molecular structure involved in the pathology of interest. Where the drug-in-development is meant to act.
