Drug counselling Flashcards
Mnemonic for drug counselling
ATHLETICS - Action; Timeline; How to take; Length of treatment; Effects before time; Tests; Important side effects; Complications/Contraindicatios; Supplementary advice
Action of Lithium
Mood stabiliser; Exact mechanism unknown; Thought to enter the cells and interfere with neurotransmitter release and second messenger systems
Timeline of Lithium
Once or twice daily depending on brand
How to take lithium
Tablet, capsule or syrup
Length of lithium treatment
Usually lifelong if it works; Regular reviews by psychiatrist
Time for effects of lithium
1-2 weeks
Pre-tests for lithium
FBC, U&Es, TFTs, betaHCG, ECG
How often to review lithium
Check after 5 days then every week until stable for 4 weeks, then every 3 months
What extra tests to review lithium
TFTs, U&Es, Ca2+ every 6 months
Important side effects of lithium
GI (abdo pain and nausea), Metallic taste, Fine tremor, Water symptoms (thirst, polyuria, impaired urinary concentration, weight gain, and oedema)
Signs of lithium toxicity
GI (anorexia, diarrhoea, vomiting); Neuromuscular (dysarthria, dizziness, ataxia, in-coordination, muscle, twitching, tremor); Others (drowsiness, apathy, restlessness)
Complications of lithium
Renal toxicity; nephrogenic diabetes insipidus; Hypothyroidism
Contraindications for lithium
1st trimester pregnancy; breastfeeding; Cardiac disease; significant renal impairment; Addison’s disease; low sodium diets; untreated hypothyroidism
Supplementary advice for lithium
www.bipolaruk.org.uk
Action of methotrexate
A disease modifying agent which both reduces inflammation and suppresses the immune system
Early use improves outcome and symptoms