Drug Classes

Question 1

Fusion Inhibitor

Answer 1

Interferes with the viruses ability to fuse with the cellular membrane, preventing HIV from entering the cell.

Question 2

Reverse Transcriptase Inhibitors

Answer 2

Prevents the HIV enzyme “reverse transcriptase” from creating single stranded HIV RNA into double stranded HIV DNA. PROCESS called reverse transcription. There are 2 types of RTI’s

Question 3

Nucleotide/Nucleoside RT Inhibitor

Answer 3

(NNRTI’S) are faulty DNA building blocks. When one of the faulty building blocks is added to a growing HIV DNA chain, no further correct DNA building blocks can be added on, thus halting HIV DNA synthesis

Question 4

Entry Inhibitor

Answer 4

Interferes with the viruses ability to bind to the receptors on the outer surface of the cell it tries to enter. When receptors binding fails, HIV cannot infect the cell.

Question 5

Non-Nucleoside RT Inhibitors

Answer 5

NNRTI’s bind to the reverse transcriptase and interfere with its ability to convert HIV RNA into HIV DNA

Question 6

Integrase Inhibitors

Answer 6

Blocks the HIV enzyme integrase, which the virus uses to integrate its genetic materials into the DNA of the cell it has infected

Question 7

Protease Inhibitors

Answer 7

Interfere with the HIV enzyme protease, which normally cuts long chains of HIV proteins into smaller individual proteins. When protease does not work properly, new virus particles cannot be assembled.

Question 8

Multi-class Combination Drug

Answer 8

Combine HIV drugs from two or more classes or types, into a single product.