Drug Calculation Flashcards
Quantitative amount administered or taken by patient for intended medicinal effect
Dose
Amount taken at one time
Single Dose
Amount taken during course of therapy
Daily Dose/ Total Dose
Schedule of Dosing (QID for 10 days)
Dosage Regimen
Amount ordinarily produces medicinal effect intended in adult patient.
Usual Adult Dose
Infant or child patient
Usual Pediatric Dose
Quantitative amounts of drugs may be prescribed within guidelines of usual medical practice.
Usual Dosage range
Amount produces desired intensity of effect 50% of indiv tested
Median Effective Dose
Amount produces toxic effects in 50% indiv tested
Median Toxic Dose
Larger than usual initial dose may be required to achieve desired blood drug level
Loading Dose (Priming dose)
Minimum concentration to produce drugs desired effect in patient
Median Effective Concentration
Concentration produces dose-related toxic effects
Minimum Toxic Concentration
Primary drug treatment
Monotherapy
Additional to or supportive of different primary treatment
Adjunctive therapy
Administered to protect patient from contracting specific diseases (ex: Vaccines)
Prophylactic Dose
- Contains pharmaceutical ingredients
- Provide physical features, stability requirement and aesthetic characteristics desired for optimal therapeutic effects
Dosage Forms
Example of Dosage Forms
solvents, vehicles, preservatives, stabilizers, solubilizers, binders
Urges the use of measuring device that either accompanies product
Dose measurement
Conversion of 1tsp
5mL
Conversion of 1tbsp
15mL
Conversion of 20 drops (gtt)
1mL
- Administration of doses that are SMALLER than usual dose of drug
- EX: low-dose oral contraceptive use
Low dose therapy
- Administration of doses that are LARGER than usual dose of drug
- High-dose use of progestin in the treatment of endometriosis
High Dose Therapy
Products containing 2 or more therapeutic agent in fixed dose combination
Fixed-Dose combination products
Advantages of Fixed dose combination
2 or more needed drugs may be taken in single dose
Disadvantages of Fixed dose combination
Inflexibility in dosing
- Number of tablets are scored, or grooved, to allow breaking into approx. equal pieces
- Allows dosage flexibility, when patients is started at half dose and then titrated up to full dosage level
Tablet Splitting and Crushing
Give the Route and DDS of
Mouth
- Oral
- tablets,capsules,oral solution, drops, syrups
Give the Route and DDS of Under the tongue
- Sublingual
- tablets
Solutions, suspension
Parenteral
Vein
Intraveneous
Artery
Intra-arterial
Heart
Intracardiac
Spine
Intraspinal/Intrathecal
Bone
Intraosseous
Joint
Intra-articular
Joint fluid
Intrasynovial
Skin
Intradermal/Subcutaneous
Muscle
Intramuscular
Skin surface
Epicutaneous
Skin surface
Epicutaneous
- Ointment, Cream, Pastes, Plasters
Eye conjunctiva
Conjunctival
- ointment
Eye
Intraocular
- solutions, suspension
Nose
Intranasal
- solutions and ointments
Ear
Aural
- solutions and suspensions (drops)
Lung
Intrarespiratory
- solution (aerosols)
Rectum
Rectal
- Solutions, ointments, suppositories
Vagina
Vaginal
- Solutions, ointments, emulsion foam
Urethra
Urethral
- Solutions and Suppositories