Drug affecting sympathetic nervous system Lecture

Question 1

α1-adrenergic receptors:
Types of adrenergic receptors
Blocked by

Answer 1

prazosin

Question 2

a1

Most of vascular smooth muscles

Answer 2

vasoconstriction (VC)

Question 3

a1

Genitourinary smooth muscles

Answer 3

contraction of trigone, sphincter.

Question 4

a1

Pupillary dilator muscle of eye

Answer 4

contraction (mydriasis).

Question 5

a1

Pilomotor smooth muscles

Answer 5

erection of hair.

Question 6

a1

Liver

Answer 6

glycogenolysis, gluconeogenesis.

Question 7

a1

Intestine

Answer 7

relaxation

Question 8

(2) α2-adrenergic receptors:

Blocked by

Answer 8

yohimbine

Question 9

a2

Vascular smooth muscles

Answer 9

vasoconstriction

Question 10

a2

B-cell of pancreas

Answer 10

→ ↓ insulin secretion

Question 11

a2

Platelets

Answer 11

aggregation

Question 12

a2

Presynaptic nerve terminals

Answer 12

↓transmitter release (↓NE).

Question 13

B1- adrenergic receptors: • Blocked by

Answer 13

atenolol

Question 14

B1- adrenergic receptors: • Blocked by atenolol.

• Heart

Answer 14

→↑ force of contraction, ↑HR ↑A-V nodal conduction.

Question 15

B1- adrenergic receptors:

Juxtaglomerular cells

Answer 15

→↑ renin secretion

Question 16

• (4) B2 - adrenergic receptors:

* Vascular, genitourinary, intestinal, bronchial smooth muscles

Answer 16

relaxation

Question 17

4) B2 - adrenergic receptors:

B-cell of pancreas →

Answer 17

→↑ insulin secretion.

Question 18

B2 adrenergic receptors:

Liver

Answer 18

→glycogenolysis, gluconeogenesis

Question 19

• (4) B2 - adrenergic receptors:

Skeletal muscles

Answer 19

→↑ contraction, K+ uptake.

Question 20

B3- adrenergic receptors:

Answer 20

Adipose tissues →↑ lipolysis due to activation of triglyceride lipase.

Question 21

all B-receptors are inhibitory (except in

Answer 21

heart

Question 22

All α- receptors are excitatory (except in

Answer 22

intestine