Drug ADRs

Question 1

Digoxin

Answer 1

GI Sx, worsened arrhythmia, bradycardia

Question 2

Amiodarone

Answer 2

GI Sx, hepatatotoxicity, worsened arrhythmia, pulmonary toxicity

Question 3

Beta blockers

Answer 3

Bradycardia, orthostatic hypotension, Hepatatotoxicity (not atenolol), GI Sx

Question 4

Antiplatelets

Answer 4

Bleeding, bruising, GI symptoms, SJ syndrome

Question 5

Heparin/Enoxaparin ADRs

Answer 5

Bleeding, bruising/infection at injection site, skin necrosis, severe thrombocytopenia

Question 6

Warfarin ADRs

Answer 6

Bleeding, bruising, skin necrosis, GI Sx

Question 7

Dabigatran, Rivaroxaban and Apixaban ADRs

Answer 7

Bleeding, bruising, hepatotoxicity, renal impairment, GI Sx

Question 8

ADRs of ACE inhibitors

Answer 8

Dry cough, hyperkalaemia, hypotension, angioedema, GI Sx

Question 9

Irbesartan

Answer 9

Dizziness, headache, hyperkalaemia, hypotension, GI Sx

Question 10

ADRs of Diuretics

Answer 10

electrolyte disturbances, orthostatic hypotension, hypokalaemia (not for spironolactone), GI Sx, rash

Question 11

Lipid lowering drug ADRS

Answer 11

Myalgia, GI Sx, rhabdomyolysis, elevated aminotransferase levels

Question 12

Dihydropyrdine ADRs

Answer 12

Vasodilatory effects (headache, flushing, dizziness), GI Sx, hypotension, peripheral oedema

Question 13

Non-dihydropyridine ADRs

Answer 13

GI Sx, bradycardia, AV block, worsening of HF