Drug Action Flashcards
0
Q
Bethanecol
A
Muscarinic agonist that is active on M3 –> improves tone and contractility of GI smooth muscle
Particularly oesophageal peristalsis in patients with reflux oesophagitis
1
Q
Bradycardia/decrease in cardiac contractility
A
Stimulate M2 recpetors in heart with nanomolar concentration of ACh -> decreases cardiac rate by
Inhibiting hyper polarisation - activated current
2
Q
GABAb receptors
A
Deficits in GABAb receptor - mediated inhibition
–> psychiatric disorders and epilepsy