Drug Action Flashcards

0
Q

Bethanecol

A

Muscarinic agonist that is active on M3 –> improves tone and contractility of GI smooth muscle
Particularly oesophageal peristalsis in patients with reflux oesophagitis

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1
Q

Bradycardia/decrease in cardiac contractility

A

Stimulate M2 recpetors in heart with nanomolar concentration of ACh -> decreases cardiac rate by
Inhibiting hyper polarisation - activated current

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2
Q

GABAb receptors

A

Deficits in GABAb receptor - mediated inhibition

–> psychiatric disorders and epilepsy

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