Dr.Lacount - Malaria - 2 Q

Question 1

Be able to state the name of insect that is responsible for transmitting malaria

Question 2

Be able to list the two organisms (genus and species) that cause the vast majority of malaria
infections. Which species cause relapses?

Question 3

Be able to describe how Plasmodium species metabolize hemoglobin, and how
aminoquinolines such quinine and chloroquine result in the buildup of toxic heme within
malaria parasite-infected cells

Question 4

Be able to discuss what is known about the mechanisms of action of the following
anti-malarial drugs
Artemisinin

Question 5

Be able to discuss what is known about the mechanisms of action of the following
anti-malarial drugs
Chloroquine

Question 6

Be able to discuss what is known about the mechanisms of action of the following
anti-malarial drugs
Primaquine

Question 7

Be able to discuss what is known about the mechanisms of action of the following
anti-malarial drugs
Doxycycline

Question 8

Be able to identify the key functional group in artemisinin and discuss what is known about
artemisinin’s mechanism of action.

Question 9

Be able to list the antimalarial drugs that are effective against the hyponozoite stage of P.
vivax

Question 10

Be able to describe how primaquine is activated.

Question 11

Be able to describe the adverse effects than can occur with chloroquine, quinine, and
primaquine.