Dr. Bhatt: MAT For Opioid Use Disorders Flashcards
Adverse Outcomes Associated with Opioid Use Disorders
- HepC
- HIV
- Unemployment
- Crime
- Overdose
- Mortality
- Cost to society
Similarities between drug addiction and other chronic diseases
- Genetic impact
- Environment also plays a role
- Long term/ chronic treatment is most effective
Which pharmacotherapies decrease mortality?
- Methadone
- Buprenorphine
- NOT shown in Naltrexone
FDA Approved medications for Opioid abuse
- Methadone
- Buprenorphine
- Naltrexone
About Methadone
-Full Mu agonist
-C2
-Highly regulated
-Difficulties:
Location of clinics
Daily dosing
Strict regulations
About Buprenorphine
-Mu partial agonist
-Lower abuse potential
-Can be prescribed by MDs, NPs, and PAs
-Strengths
Requires less frequent office visits
Allows pt more free time
-Less risk for abuse
About Naltrexone
- Mu antagonist
- Oral pill is NOT effective
- Use long acting injection Q4weeks
- Have to wait a long time to give first dose
- Very expensive
- No addictive potential
Does dependence occur with these treatments
- Yes it can
- But dependence and addiction are two very different creatures
How long do I stay in treatment
- The longer the better!
- If pt really wants to get off of the meds; set goals, taper the patient off
- Monitor closly
Recovery
- Sobriety
- Improved quality of life
- Reclaiming yourself!
What was found from the MOTHER trial
- Babies exposed to methadone need more morphine to treat the NAS
- They also had longer hospital stays
What drug are medical professionals allowed to be treated with if they have an opioid addiction?
-ONLY naltrexone
Signs and Symptoms of Opioid withdrawal
- Runny Nose
- Dilated pupil
- Goose bumps
What is the time line of withdrawal from heroin
- Onset: 6 to 12hrs
- Duration: 5 days
