Dr Asif Lang Flashcards

1
Q

Phf gives rise to

A

Atria and lv

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2
Q

Shf gives

A

Rv, outfow tract

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3
Q

Shf laterality

A

Left for right

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4
Q

Dorsal aortae

A

Other than cardiogenic area thst gives lateral blood islands that unite to form da

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5
Q

Antidepressants are teratogenic

A

Distrupt serotinin pw, pitx.

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6
Q

Pitx2

A

Master gene for left sidedness

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7
Q

Initially heart tube connects to dorsal pericarfdial cavity by

A

D. Mesocardium

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8
Q

D mesocardium looses inner part and becomes

A

Transverse pc sinus

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9
Q

Cardiac jelly is rich in

A

Hyaluronic acid

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10
Q

Card tube begins to bend by and ends by

A

Day 23 ends by 28

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11
Q

Reason of loopin

A

Cells being added continuously, inc length, less space so bends

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12
Q

B. Cordis gives

A

Trab part of rv

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13
Q

C . Cordis gives

A

Outflow tract of both vent

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14
Q

Truncus arteriosus gives

A

Roots and proximal parts of aorta and pa

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15
Q

Proximal 3rd of bulbus yives

A

Prim rv while rest gives prim lv

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16
Q

Sonic hedge hog pathway

A

Elongation of outflow tract

17
Q

S. Venosus veins

A

Vitellrne or omphalomesentric
Umbilical
Common cardinal ant and post

18
Q

Left to right shunt in _____ weeks?
Changes?

A

4th to 5th
Left horn shrinkage and right umbilical vein disappears

19
Q

Remnants of left horn

A

Coronary sinus
Oblique left atrium vein

20
Q

Right horn gives

A

Smooth part of RA= sinus venarum

21
Q

Sinu atrial orifice has____ valves

A

Righ left venous valves

22
Q

Crista terminalis

A

Sep smooth trab parts of ra

23
Q

Septa formation tim3

A

27 to 37 days

24
Q

Ostium primum

A

Opening btw R and L atria formed by septum primum

25
Q

Before spt prim7m closure

A

Apoptosis leaves a hole, ostium secondum

26
Q

Smooth part of ra is given by s. Venosus
While la is given by the pulmonary veins

27
Q

Av valves derived from

A

Mesenchymal tissue

28
Q

Common teratogens

A

Rubella, thalidomide,alcohol, insulin dependent diabetes

29
Q

Hypoplastic sybdrome

A

Less cells in one chamber

30
Q

Ebstein anomaly

A

Tricuspid valve moves to apex

31
Q

Neural crest cells a.so contribute to facial development so heart and facial defects togethrr are common

32
Q

Most common heart defects

33
Q

TOF

A

1 pulmonary stenosis
2 iv septal defect
3 overriding aorta over the defect
4 right vent hypertrophy

34
Q

TOF is commonky found in people with

A

Alagile syndrome

35
Q

Pacemaker system development

A

First all cells have the ability then caudal end of heart tube yhen sinus venoaua then san

36
Q

Aortic arches

A

Supply of corresponding pharyngeal arches

37
Q

Aortic arches no

A

5 pairs, fifth almost never forms

38
Q

Vasculoendothelial factor

A

Patterning of vascular sys

39
Q

Remaining arches by day 29