Double Helix DNA Structure Flashcards

1
Q

Double helix Structure was given by

A

Watson and Crick

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2
Q

The double helix structure was based on a study of

A
  1. (Franklin and Wilkins ) => X-ray diffraction of DNA =>Crystallography of DNA => Observed DNA in the form of Helix
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3
Q

DNA shows ————periodicity

A

3.4 Angstrom

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4
Q

Width of ONE DNA ()

A

20 Angstrom

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5
Q

Length of One Gene ()

A

3.4 Angstrom

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6
Q

3.4 A is how many nm

A

0.34 nm

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7
Q

Distance between two successive base pairs in DNA is

A

0.34 nm/ 3.4 A

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8
Q

Chargaff Rule

A

the molar concentration of Purine should be equal to Pyrimidine..

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9
Q

CHARGAFF RULE

A

[A+G/C+T]

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10
Q

[A+G/C+T] , this base ratio is —————– in different organisms

A

DIFFERENT

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11
Q

DNA is ———————-Stranded

A

DOUBLE

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12
Q

DNA backbone is made up of

A

S-P-S (Sugar Phosphate Sugar), Nitrogenous Bases Projected Inwards

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13
Q

Nitrogenous bases are projected

A

INWARDS

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14
Q

DNA shows —————-Base pairs

A

Complementary (A will always bond with T and G with C)

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15
Q

DNA is always —————-handed helix

A

Right handed

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16
Q

Both strands are ——–to each other

A

Anti Parallel

17
Q

Stability of DNA is provided by

A

Hydrogen Bond (Plane of Base pairs is stacked over each other)

18
Q

DNA is ————-in nature

19
Q

DNA is —————- charged

A

Negatively charged

20
Q

Number of base pairs in human dna

A

6.6 * 10 power 9

21
Q

DNA is wrapped around ————————

A

Histone core

22
Q

histone core

A

Histone Octomer Core

23
Q

DNA wrapped around histone octamer core is called

A

Nucleosome

24
Q

Histone is ———-core

25
Octomar means
made from one protein
26
Octomar core
has 2 molecules of H2A, H2B, H3 and H4
27
1 Nucleosome has -----------bp long DNA
200 Bp
28
The procedure of DNA Coiling
First Coiling(DNA Thread) => Then DNA is circled around histone (Called Nucleosome) => then the DNA is made like a telephone cord (Called Solenoid/Chromatin Fibre) 30 nm => more coiling (called super coiled=> then DNA looks diploid =>then on division it forms chromosomes
29
2 molecules of H2A, H2B, H3H4 are genes or not
No, they arent genes of octomar protein. they are just the units of octomer protein
30
What is the C-value of DNA
Total AMount of DNA