Dosing Values

Question 1

Sacubitril/Valsartan (Entresto)

Answer 1

Starting dose: 24/26 mg - 49/51 mg twice daily

Target dose: 97/103 mg twice daily

Question 2

Lisinopril (Prinivil/Zestril)

Answer 2

Starting dose: 2.5-5 mg daily

Target dose: 20-40 mg daily

Question 3

Losartan (Cozaar)

Answer 3

Starting dose: 25-50 mg daily

Target dose: 150 mg daily

Question 4

Valsartan (Diovan)

Answer 4

Starting dose: 40 mg twice daily

Target dose: 160 mg twice daily

Question 5

Bisoprolol (Zebeta)

Answer 5

Starting dose: 2.5 mg daily

Target dose: 10 mg daily

Question 6

Metoprolol succinate (Toprol XL)

Answer 6

Starting dose: 12.5-25 mg daily

Target dose: 200 mg daily

Question 7

Carvedilol (Coreg)

Answer 7

Starting dose: 3.125-6.25 mg twice daily

Target dose: 25 mg twice daily; >85 kg: 50 mg twice daily

Question 8

Eplerenone

Answer 8

Starting dose: 25 mg daily

Target dose: 50 mg daily

Question 9

Spironolactone

Answer 9

Starting dose: 12.5-25 mg daily

Target dose: 25-50 mg daily

Question 10

Dapagliflozin

Answer 10

Starting dose/Target dose: 10 mg

Question 11

Empagliflozin

Answer 11

Starting dose/Target dose: 10 mg

Question 12

Hydralazine (Apresoline)

Answer 12

Starting dose: 25 mg tid

Target dose: 75 mg tid

Question 13

Isosorbide dinitrate

Answer 13

Starting dose: 20 mg tid

Target dose: 40 mg tid

Question 14

BiDil (20 mg isosorbide dinitrate + 37.5 mg hydral)

Answer 14

Starting dose: 1 tablet tid

Target dose: 2 tablets tid

Question 15

Clopidogrel

Answer 15

Loading dose: 300-600 mg; if PCI give 600 mg ASAP; if STEMI with thrombolytic 300 mg but 75 mg if > 75 years of age
Maintenance dose: 75 mg daily

Question 16

Prasugrel

Answer 16

Loading dose: 60 mg with PCI

Maintenance: 10 mg daily; 5 mg if <60 kg or >75 years of age

Question 17

Ticagrelor

Answer 17

Loading dose: 180 mg

Maintenance dose: 90 mg bid; 60 mg bid after 12 months