Dosing regimen

Question 1

Uncomplicated UTI

Answer 1

1. SXT 960mg BD x 3d
   NFT 50g QDS x 5days
   Fosfo 3g 1 dose
2. Aug 625mg BD
   Cephalexin 250mg BD
   Cefuroxime 250mg BD
   X 5-7 DAYS
3. Cipro 250mg BD
   Levo 250mg OD
   X 3DAYS

Question 2

What forces u not to use first line uncomplicated UTI (SXT, NFT, fosfo)

Answer 2

• g6pd (cannot use SXT and NFT)
• CrCl < 15, cannot use SXT and NFT
• CrCl < 30, cannot use SXT
• pregnant (SXT 1st term, last term), lactation (SXT), near term (NFT)
• ## sulfa allergy, folate deficiency (SXT)

Question 3

What forces u not to use second line uncomplicated UTI (b-lactam)

Answer 3

Hypersensitivity
Aug: hepatitis, cholestatic jaundice.
Cephalexin, cefuroxime: nth much

Question 4

Complicated UTI treatment length

Answer 4

7days SXT
7-14days NFT
3 dose EOD Fosfo

12-14days beta-lactam

7-14days cipro, levo

Question 5

Pyelonephritis women

PYELO WOMEN PO QSAC(LX)
IV G-C(ipro)C(zl)A

Answer 5

PO
1. Cipro 500mg BD
Levo 750mg OD

Aug 625mg TDS
SXT
Cephalexin 500mg BDS

10-14DAYS

IV
2. cefazolin 1g q 8hr, aug 1.2g q 8hr, cipro 400mg BD +/- gentamicin 5mg/kg/day

Question 6

nosocomial pyelo

Answer 6

IV:
1. Cefepime 2g q12hr + amikacin 15mg/kg/day

Imi 500mg q6hr
Mero 1g q8hr

PO:
2. Cipro 500mg BD
Levo 750mg OD

FOR 7-14 DAYS

Question 7

Men

Answer 7

complicated uti in women

With suspected prostatis or pyelo
Cipro 500mg bd
SXT 960mg BD

FOR 10-14DAYS

Question 8

Length

Answer 8

PMNC
Pregnant 7 or 14
Men 10-14
Nosocomial 7-14
Catheter 7 or 10-14

Question 9

CA-UTI

Answer 9

If stable with low grade fever (37.8-38.1) , monitor and change catheter

If sx (fever, rigor, malaise, flank pain, cortovetebral angle, hematuria) -
1. Cefepime 1g q8hr +/- amikacin 15mg/kg (1dose)
2. Imi
Mero

FOR 7/ 10-14 (FOR THOSE WITH DELAYED RESPONSE)

3. Levo (IV/PO) 750mg OD for 5 days!!!
4. If mild UTI in a women below 65 yo, and remove catheter, no pyelo: can use sxt 960mg BD for 3 days