Dosing Flashcards
Phenytoin
Usual maintenance dose (mg/day)
Phenytoin
Usual maintenance dose (mg/day)
300-400 (or 5-7 mg/kg/day)
Sodium valproate
Usual maintenance dose (mg/day)
Sodium valproate
600-2000* (or 20-30 [max. 60] mg/kg/day)
No need for dose adjustment in (usually severely) impaired renal function
Carbamazepine
Usual maintenance dose (mg/day)
Carbamazepine
Usual maintenance dose (mg/day)
800-1200
Phenobarbitone
Usual maintenance dose (mg/day)
Phenobarbitone
Usual maintenance dose (mg/day)
60-180
Lamotrigine
Usual maintenance dose (mg/day)
Lamotrigine
Usual maintenance dose (mg/day)
100-200
Topiramate
Usual maintenance dose (mg/day)
Topiramate
Usual maintenance dose (mg/day)
200-400
Levetiracetam
Usual maintenance dose (mg/day)
Levetiracetam
Usual maintenance dose (mg/day)
1000-3000
Gabapentin
Usual maintenance dose (mg/day)
Gabapentin
Usual maintenance dose (mg/day)
900-1800
Vigabatrine
Usual maintenance dose (mg/day)
Vigabatrine
Usual maintenance dose (mg/day)
1000-2000
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Phenytoin
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Phenytoin 10-20 (corrected, albumin)
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Sodium valproate
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Sodium valproate
50-100
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Carbamazepine
4-12
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Phenobarbitone
Phenobarbitone
10-40
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Lamotrigine
Lamotrigine
4-18
Therapeutic Drug Monitoring
Usual therapeutic drug concentrations (mg/L)
Ethosuximide
Ethosuximide
300-700