Dosing

Question 1

Metformin

Answer 1

(Regular release)
Start: 500 - 850 mg OD, max 2.5 - 2.55 mg daily

(Extended release)
Start: 500 mg OD, max 2 g OD

Question 2

Glipizide

Answer 2

5 mg BD, max 40 mg daily

Question 3

Thiazolidinediones

Answer 3

(Rosiglitazone)
4 mg OD, max 8 mg daily

(Pioglitazone)
15 or 30 mg OD, max 45 mg OD

Question 4

Acarbose

Answer 4

25 mg BD-TDS
(60 kg and below) max 100 mg daily
(>60 kg) max 300 mg daily

Question 5

GLP-1 agonists

Answer 5

Liraglutide: 0.6 mg OD -> 1.2 mg -> 1.8 mg
Dulaglitide: start 0.75 - 1.5 mg once weekly
Semaglutide: start 3 mg daily -> 7 mg 30 days later

Question 6

DPP 4 inhibitors

Answer 6

Sitagliptin: 100 mg OD
Linagliptin: 5 mg OD

Question 7

SGLT2 inhibitors

Answer 7

Cana: 100-300 mg OD
Empa: 10-25 mg OD
Dapa: 5-10 mg OD