Doses, DOA, Onset... Flashcards
Succinylcholine onset
30-60s
Succinylcholine DOA
5-10min
Succinylcholine ED95
0.25-0.5 mg/kg
Succinylcholine Intubating
1-1.5mg/kg (1.5mg/kg for rapid sequence)
Pancuronium Bromide ED95
0.07mg/kg
Pancuronium Bromide Intubating Dose
0.1 mg/kg
Pancuronium Bromide Onset
3-5 min (slow)
Pancuronium Bromide DOA
60-90 min (long)
Doxacurium (Benzylisoquinolinium) ED95
0.03 mg/kg
Doxacurium (Benzylisoquinolinium) Onset
4-6 min
Doxacurium (Benzylisoquinolinium) DOA
60-90 min
Pipercuronium (Bisquaternary aminosteroid) ED 95
0.055 mg/kg
Pipercuronium (Bisquaternary aminosteroid) Onset
3-5 min
Pipercuronium (Bisquaternary aminosteroid) DOA
60-90 min
Vercuronium Bromide ED95
0.05 mg/kg
Vercuronium Bromide (intubating dose)
0.1 mg/kg
Vercuronium Bromide onset
3-5 min
Vercuronium Bromide DOA
20-35 min
Rocuronium Bromide ED95
0.3 mg/kg
Rocuronium Bromide (induction dose)
0.6 mg/kg (rapid: 1.2 mg/kg)
Rocuronium Bromide onset
1-2 min (rapid: 30-45 sec)
Rocuronium Bromide DOA
20-35 min (rapid: 60-90 min)
Atracurium Bromide ED95
0.2 mg/kg
Atracurium Bromide (intubating dose)
0.5 mg/kg
Atracurium Bromide onset
3-5 min
Atracurium Bromide DOA
20-35 min
Cistracurium Bromide ED95
0.05 mg/kg
Cistracurium Bromide (intubating dose)
0.2 mg/kg
Cistracurium Bromide onset
3-5 min
Cistracurium Bromide DOA
20-35 min
Mivacurium ED95
0.08 mg/kg
Mivacurium (intubating dose)
0.25 mg/kg
Mivacurium onset
2-3 min
Mivacurium DOA
12-20 min
Midazolam (induction)
0.1-0.3 mg/kg
% solution
g/100ml
Methohexital Induction
- 1-1.5 mg/kg
- peds: 1-2mg/kg
- peds rectal: 20-30 mg PR
Lorazapam
50 mcg/kg (up to 4 mg)
Propofol (induction)
- 1.5-2.5 mg/kg IV
- peds: 2-3 mg/kg IV
- elderly 25-50% dose reduction
Propofol (maintenance dosing)
- 100-300 mcg/kg/min
- peds book 60-250 mcg/kg/min
- peds reeality 200-400 mcg/kg/min
Propofol (IV sedation)
25-100 mcg/kg/min
2 mg/kg/hr for amnesia unstimulated =33mcg/kg/min
Propofol PONV
10-15mg PACU
Propofol (anti-epilectic)
2 mg/kg bolus
Etomidate (induction)
0.2-0.4 mg/kg
Ketamine (induction)
- 1-2 mg/kg IV bolus
- 4-8 mg/kg IM
Sodium Thiopentol Induction
- 3-5 mg/kg IV (decrease 18% pregnancy)
- 5-6 mg/kg IV peds
Methylnatrexone
0.3 mg/kg
Nalmefene
0.2-2 mg/kg
Natrexone
0.2-2 mg/kg
Naloxone
1-4 mcg/kg
DOA 30-45 min
infusion 5 mcg/kg/hr
Hydromorphone
1.5 mg= 10mg Morphine
Midazolam IV sedation
1-2.5 mg IV bolus
Flumazanil
0.2mg IV (titrate 0.1mg to effect, max 1mg)
Remifentanil (infusion)
0.05-2 mcg/kg/min
Remifentanil (sedation with benzo)
0.05-0.1 mcg/kg/min
Remifentanil (pre-induction)
1 mcg/kg over 60-90sec
Midazolam (peds, sedation and anxiolysis)
- 5 mg/kg PO 30 min before case
0. 05-1 mg/kg IM
Fentanyl analgesia/sedation
1-2 mcg/kg
Fentanyl induction
2-20 mcg/kg
1-5mcg/kg
balanced- 1.5-3 mcg/kg decreases IA by 50%
Diazepam anticonvulsant
0.1 mg/kg IV
Diazepam IV sedation
0.05-0.15 mg/kg
Sufentanil O-P-D
o- 3min
p- 7min
d- 0.5-1hrs
Diazepam Induction
0.3-0.5 mg/kg
Diazepam (sedation and anxiolysis PO)
10-15 mg PO
Meperidine O-P-D
o- <1min
p- 5-7min
d- 2-3hrs
Morphine O-P-D
IV:
o- 5min
p-15-20min
d- 3-4hrs
IM:
o- 15-30min
p- 45min
Fentanyl O-P-D
o- 2min
p- 5-7min
d- 45min
Alfentanil O-P-D
o- 30 sec
p-1.5-2min
d- 15min
Remifentanyl O-P-D
o- 0.5-1min
p- 1.5-2min
d- 10min
Neostigmine
Up to 0.07 mg/kg (but no more than 5 mg total dose)
Pyridostigmine
up to 0.35 mg/kg (up to 20 mg in adults)
Endrophonium
1 mg/kg
Physostigmine
0.03 mg/kg
Atropine (premedication)
-0.01-0.04 mg IM (up to 0.4-0.6 mg total, adults)
Atropine (minimize muscarinic effects of anticholiesterases)
up to 10 mcg/kg (with endrophonium)
Scopalamine (premedication)
0.4-0.6 mg/kg IM
Glycopyrrolate (premedication)
up to 0.3 mg IM
Glycopyrrolate (minimize muscarinic effects of anticholinesterases)
0.01-0.12 mcg/kg
Neostigmine: 1 mg 2 mg 3 mg 4 mg 5 mg
Glycopyrrolate:
- 2 mg (4/4 with ST)
- 4 mg (4/4)
- 6 mg (3/4)
- 7 mg (2/4)
- 8 mg (1/4)
Physiostigmine (treatment central anticholinergic syndrome)
15-60 mcg/kg IV
