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Pharmacology > Doses, DOA, Onset... > Flashcards

Doses, DOA, Onset... Flashcards

1
Q

Succinylcholine onset

A

30-60s

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2
Q

Succinylcholine DOA

A

5-10min

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3
Q

Succinylcholine ED95

A

0.25-0.5 mg/kg

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4
Q

Succinylcholine Intubating

A

1-1.5mg/kg (1.5mg/kg for rapid sequence)

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5
Q

Pancuronium Bromide ED95

A

0.07mg/kg

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6
Q

Pancuronium Bromide Intubating Dose

A

0.1 mg/kg

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7
Q

Pancuronium Bromide Onset

A

3-5 min (slow)

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8
Q

Pancuronium Bromide DOA

A

60-90 min (long)

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9
Q

Doxacurium (Benzylisoquinolinium) ED95

A

0.03 mg/kg

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10
Q

Doxacurium (Benzylisoquinolinium) Onset

A

4-6 min

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11
Q

Doxacurium (Benzylisoquinolinium) DOA

A

60-90 min

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12
Q

Pipercuronium (Bisquaternary aminosteroid) ED 95

A

0.055 mg/kg

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13
Q

Pipercuronium (Bisquaternary aminosteroid) Onset

A

3-5 min

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14
Q

Pipercuronium (Bisquaternary aminosteroid) DOA

A

60-90 min

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15
Q

Vercuronium Bromide ED95

A

0.05 mg/kg

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16
Q

Vercuronium Bromide (intubating dose)

A

0.1 mg/kg

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17
Q

Vercuronium Bromide onset

A

3-5 min

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18
Q

Vercuronium Bromide DOA

A

20-35 min

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19
Q

Rocuronium Bromide ED95

A

0.3 mg/kg

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20
Q

Rocuronium Bromide (induction dose)

A

0.6 mg/kg (rapid: 1.2 mg/kg)

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21
Q

Rocuronium Bromide onset

A

1-2 min (rapid: 30-45 sec)

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22
Q

Rocuronium Bromide DOA

A

20-35 min (rapid: 60-90 min)

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23
Q

Atracurium Bromide ED95

A

0.2 mg/kg

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24
Q

Atracurium Bromide (intubating dose)

A

0.5 mg/kg

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25
Q

Atracurium Bromide onset

A

3-5 min

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26
Q

Atracurium Bromide DOA

A

20-35 min

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27
Q

Cistracurium Bromide ED95

A

0.05 mg/kg

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28
Q

Cistracurium Bromide (intubating dose)

A

0.2 mg/kg

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29
Q

Cistracurium Bromide onset

A

3-5 min

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30
Q

Cistracurium Bromide DOA

A

20-35 min

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31
Q

Mivacurium ED95

A

0.08 mg/kg

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32
Q

Mivacurium (intubating dose)

A

0.25 mg/kg

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33
Q

Mivacurium onset

A

2-3 min

34
Q

Mivacurium DOA

A

12-20 min

35
Q

Midazolam (induction)

A

0.1-0.3 mg/kg

36
Q

% solution

A

g/100ml

37
Q

Methohexital Induction

A
  • 1-1.5 mg/kg
  • peds: 1-2mg/kg
  • peds rectal: 20-30 mg PR
38
Q

Lorazapam

A

50 mcg/kg (up to 4 mg)

39
Q

Propofol (induction)

A
  • 1.5-2.5 mg/kg IV
  • peds: 2-3 mg/kg IV
  • elderly 25-50% dose reduction
40
Q

Propofol (maintenance dosing)

A
  • 100-300 mcg/kg/min
  • peds book 60-250 mcg/kg/min
  • peds reeality 200-400 mcg/kg/min
41
Q

Propofol (IV sedation)

A

25-100 mcg/kg/min

2 mg/kg/hr for amnesia unstimulated =33mcg/kg/min

42
Q

Propofol PONV

A

10-15mg PACU

43
Q

Propofol (anti-epilectic)

A

2 mg/kg bolus

44
Q

Etomidate (induction)

A

0.2-0.4 mg/kg

45
Q

Ketamine (induction)

A
  • 1-2 mg/kg IV bolus

- 4-8 mg/kg IM

46
Q

Sodium Thiopentol Induction

A
  • 3-5 mg/kg IV (decrease 18% pregnancy)

- 5-6 mg/kg IV peds

47
Q

Methylnatrexone

A

0.3 mg/kg

48
Q

Nalmefene

A

0.2-2 mg/kg

49
Q

Natrexone

A

0.2-2 mg/kg

50
Q

Naloxone

A

1-4 mcg/kg
DOA 30-45 min
infusion 5 mcg/kg/hr

51
Q

Hydromorphone

A

1.5 mg= 10mg Morphine

52
Q

Midazolam IV sedation

A

1-2.5 mg IV bolus

53
Q

Flumazanil

A

0.2mg IV (titrate 0.1mg to effect, max 1mg)

54
Q

Remifentanil (infusion)

A

0.05-2 mcg/kg/min

55
Q

Remifentanil (sedation with benzo)

A

0.05-0.1 mcg/kg/min

56
Q

Remifentanil (pre-induction)

A

1 mcg/kg over 60-90sec

57
Q

Midazolam (peds, sedation and anxiolysis)

A
  1. 5 mg/kg PO 30 min before case

0. 05-1 mg/kg IM

58
Q

Fentanyl analgesia/sedation

A

1-2 mcg/kg

59
Q

Fentanyl induction

A

2-20 mcg/kg
1-5mcg/kg

balanced- 1.5-3 mcg/kg decreases IA by 50%

60
Q

Diazepam anticonvulsant

A

0.1 mg/kg IV

61
Q

Diazepam IV sedation

A

0.05-0.15 mg/kg

62
Q

Sufentanil O-P-D

A

o- 3min
p- 7min
d- 0.5-1hrs

63
Q

Diazepam Induction

A

0.3-0.5 mg/kg

64
Q

Diazepam (sedation and anxiolysis PO)

A

10-15 mg PO

65
Q

Meperidine O-P-D

A

o- <1min
p- 5-7min
d- 2-3hrs

66
Q

Morphine O-P-D

A

IV:
o- 5min
p-15-20min
d- 3-4hrs

IM:
o- 15-30min
p- 45min

67
Q

Fentanyl O-P-D

A

o- 2min
p- 5-7min
d- 45min

68
Q

Alfentanil O-P-D

A

o- 30 sec
p-1.5-2min
d- 15min

69
Q

Remifentanyl O-P-D

A

o- 0.5-1min
p- 1.5-2min
d- 10min

70
Q

Neostigmine

A

Up to 0.07 mg/kg (but no more than 5 mg total dose)

71
Q

Pyridostigmine

A

up to 0.35 mg/kg (up to 20 mg in adults)

72
Q

Endrophonium

A

1 mg/kg

73
Q

Physostigmine

A

0.03 mg/kg

74
Q

Atropine (premedication)

A

-0.01-0.04 mg IM (up to 0.4-0.6 mg total, adults)

75
Q

Atropine (minimize muscarinic effects of anticholiesterases)

A

up to 10 mcg/kg (with endrophonium)

76
Q

Scopalamine (premedication)

A

0.4-0.6 mg/kg IM

77
Q

Glycopyrrolate (premedication)

A

up to 0.3 mg IM

78
Q

Glycopyrrolate (minimize muscarinic effects of anticholinesterases)

A

0.01-0.12 mcg/kg

79
Q 
Neostigmine:
1 mg
2 mg
3 mg
4 mg
5 mg
A

Glycopyrrolate:

  1. 2 mg (4/4 with ST)
  2. 4 mg (4/4)
  3. 6 mg (3/4)
  4. 7 mg (2/4)
  5. 8 mg (1/4)
80
Q

Physiostigmine (treatment central anticholinergic syndrome)

A

15-60 mcg/kg IV

Pharmacology (9 decks)

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