Dosages Flashcards
Epi Grade II treatment
10-20 mcg SC/IM
Vasopressin anaphylaxis treatment
2 - 10 units for epinephrine unresponsiveness
Epi grade III treatment
100-200 mcg SC/IM/IV q1-2 mins;
1-4 mcg/min (infusions)
Epi grade IV Treatment
1 mg IV repeat as needed
4-10 mcg/min infusion
Anaphylactic treatment:
pre-op beta blockade w/ Glucagon
1-5 mg IV q 5 min;
5-15 mcg/min
Anaphylactic treatment:
H1 - benadryl treatment
0.5-1 mg/kg (max 50 mg)
Anaphylactic treatment:
H2 – famotidine (Pepcid)
20 mg
Anaphylactic treatment:
Terbutaline
0.25 mg SC
may repeat in 15-30 mins
Anaphylactic treatment:
hydrocortisone
250 mg IV
Anaphylactic treatment:
adjunct epi infusion
0.05 – 0.1 mcg/kg/min
Anaphylactic treatment:
adjunct NorEpi infusion
0.05 – 0.1 mcg/kg/min
Anaphylactic treatment:
adjunct NaBicarb
0.5 – 1 mEq/kg initially, then titrate to ABGs
daily corticosteroid release (normal)
20 mg daily with more secreted during the day and less at night
The Stress response – output increases secretion to how much?
200 mg daily
50 mg/day – minor surgery
75-150 mg/day – major surgery
Elimination ½ life of corticosteroid release
70 minutes
NO STORAGE
minor surgery steroid coverage dosing
Preoperative corticosteroid dose + hydrocortisone 25 mg or equivalent
moderate surgery steroid coverage dosing
Preoperative corticosteroid dose + hydrocortisone 50-75 mg or equivalent; taper by 50% per day over 1-2 days
major surgery steroid coverage dosing
Preoperative corticosteroid dose + hydrocortisone 100-150 mg, taper by 50% per day over 1-2 days
antiemetic of dexamethasone dose
0.5 mg/kg
best if given before induction
Prochlorperazine (Compazine) dosing:
2.5 - 10 mg IV
promethazine (Phenergan)
25 mg IV
scopolamine antiemetic dosing
apply patch 60 mins prior to induction
5 mcg/hr for 72 hours
total dose absorbed less than 0.5 mg
Butyrophenones (droperidol, Inapsine)
0.625 - 1.25 mg IV
(watch for prolonged QT interval)
Metoclopramide (Reglan)
10 - 20 mg IV
