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Therapeutics Module 3 > Dosages > Flashcards

Dosages Flashcards

1
Q

Anemia

Typical HgB Levels for women (low)

A

Less then 120

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2
Q

Anemia

Typical HgB levels for men (low)

A

Less then 130mg

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3
Q

Anemia

HB concentrations need to increase at a rate of?

A

10g/L per week

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4
Q

Anemia

Weight based dosing for Pediatrics?

A

3-6mg/kg/d divided TID

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5
Q

Anemia

Target intake of B12 in women?

A

2.4-2.8mcg

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6
Q

Anemia

Typical B12 dosing to normalize B12?

A

100uf

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7
Q

Anemia

Typical dosing regimen for B12 for deficiency (SC)

A

30ug daily for 5-10 days

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8
Q

Anemia

Typical dosing regimen for B12 for deficiency (Oral)

A

500-2000ug

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9
Q

Anemia

Typical dosing regimen for maintenance B12?

A

SC: 100-200ug (Monthly
Oral 250ug daily

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10
Q

Anemia

Typical B12 dosage for Pernicous anemia?

A

100ug daily for 1 week,
200ug weekly untill Hb normalized

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11
Q

Anemia

Lifelong maintenance for B12 with respect to pernicous anemia?

A

100ug monthly SC/IM
1000-2000 orally daily

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12
Q

Anemia

Typical daily requirements of folate for women/pregnant/lactation

A

400-600ug

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13
Q

Anemia

Typical dose for Folic acid deficiency?

A

1mg/day or 5mg/day if absorption compromised

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14
Q

VTE

Typical dosing of heparin for prophylaxis

A

5000 units SC q8-12 hours

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15
Q

VTE

Typical dosing for treatment of DVT IV heparin

A

LD 80 units/kg over 10 minutes, 18units kg/hour

SC 250units/kg Q12H

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16
Q

VTE

Typical dosing of tinzaparin for prophylaxis

A

75 units/kg (sometimes 4500)

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17
Q

VTE

Typical dosing for tinzaparin for VTE treatment

A

175 units/kg for VTE treatment

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18
Q

VTE

Typical dosing for tinzaparin for dialysis line treatment?

A

2500 units

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19
Q

VTE

Three drugs we should know for the treatment of HIT?

A

Danaparoid
Fondaparinux
Argatroban

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20
Q

VTE

Typical dosing regimen start for warfarin?

A

2-3mg OD, 5mg OD, 10mg OD (All for 2 days as separate regimens)

INR SPECIFIC DOSING

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21
Q

VTE

Drugs used to reverse the effects of warfarin?

A

Vitamin K 5-10mg IV q12h
Factor IV prothrombin complex or FFP

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22
Q

VTE

Which DOAC has the highest duration of effect?

A

Rivaroxaban 9h
Apixaban 8-14 hour
Dabigatran 13hr, 18hr in renal imparment
Edoxaban 14h

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23
Q

VTE

What is Rivaroxaban recurrent VTE prevention?

A

10-20mg daily (Higher with food)

24
Q

VTE

Apixaban dosing for recurrent VTE prevention

A

2.5mg BID

25
Q

VTE

Dabigatran dosing for recurrent VTE prevention

A

150mg BID

26
Q

VTE

Rivaroxaban dosing for treatment of VTE?

A

15mg BID for 3 weeks, then 20mg daily

27
Q

VTE

Apixaban dosing for treatment of VTE?

A

10mg BID for 7 days. then 5mg BID

28
Q

VTE

Dabigatran dosing for treatment of VTE

A

Must recieve 5-10 days of subcut anti-coagulant (LMWH/heparan), then 150mg BID

29
Q

VTE

Edoxaban treatment of VTE?

A

60mg once daily after bridging for 5-10 days

Low weight gets 30mg

30
Q

VTE

Dosing strategies of DOACS in >BMI

A

Avoid dabigatrand and edoxaban. No real dosing adjustments required though

31
Q

VTE

What drugs are safe to use in pregnancy for VTE prophylaxis

A

UFH, LMWH, Danaparoid, Fondaparinux

32
Q

VTE

What is the lowest renal dosing allowable for Apixaban?

A

> 25

33
Q

VTE

What is the lowest renal dosing allowable for Dabigatran

A

> 30

34
Q

VTE

What is the lowest renal dosing allowable for Edoxaban

A

> 30

35
Q

VTE

What is the lowest renal dosing allowable for Edoxaban

A

> 30

36
Q

VTE

What is the lowest renal dosing allowable for Rivaroxaban

A

> 30

37
Q

HF

What is the TD of Enalapril

A

10mg BID (20mg BID for NYHA IV)

38
Q

HF

What is the TD of Lisinopril

A

20-35mg daily

39
Q

HF

What is the TD of Perindopril

A

4-8mg daily

40
Q

HF

What is the TD of Ramipril

A

5mg BID

41
Q

HF

What is the TD of Trandalopril

A

4mg daily

42
Q

HF

What is the TD of Candesartan

A

32mg Daily

43
Q

HF

What is the TD of Valsartan

A

160mg BID

44
Q

HF

What is the TD of Entresto

A

200mg BID

45
Q

HF

What is the TD of Carvediolol

A

25mg BID or 50mg BID >85kg

46
Q

HF

What is the TD of Bisoprolol

A

10mg daily

47
Q

HF

What is the TD of Metoprolol (CR/XL)

A

200mg daily

48
Q

HF

What is the TD of Sprionolactone

A

25-50mg daily

49
Q

HF

What is the TD of Eplerenone

A

50mg

MRA

50
Q

HF

What is the TD of Dapaglfilozin

A

10mg daily

51
Q

HF

What is the TD of Empagliflozin?

A

10mg daily

52
Q

HF

What is the TD of Ivabradine

A

7.5mg BID

53
Q

HF

What is the TD of Digoxin

A

Not a target dose but between 0.0625-0.2mg

54
Q

HF

What is the TD of Vericiguat

A

10mg daily

55
Q

HF

What is the TD of Hydralazine-nitrates

A

Hydralazine 75-100mg TID or QID

Nitrate 40mg TID

Therapeutics Module 3 (6 decks)

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