dosage forms + administration routes Flashcards
Why develop dosage forms?
1) convenience
2) safety
3) efficacy
4) accuracy
5) reproducability
API
active pharmaceutical ingredient
excipient
ingredient in a dosage form that does not have a pharmacological action but have a specific function
Why would you not administer an active pharmaceutical ingredient (API) to a patient in its pure form?
1) it would be inconvenient
2) it would not guarantee drug stability
3) it would be difficult to give an accurate dose
4) it would not be safe
disintegrating agent
makes sure the tablet breaks in the gastrointestinal tract (GIT) to release the drug
solubilising agent
enhances the solubility of poorly soluble drugs
bulking agent
makes the tablet bulkier + easier to compress
protective (enteric) coating
protects the tablet from breaking in the stomach if a drug is acid labile