Dosage Form Excipients Flashcards

1
Q

solvents

A

water, vegetable oils

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2
Q

co solvents / humectant

A

ethanol, glycerin, propylene glycol

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3
Q

sweetner

A

sucrose, sorbitol

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4
Q

buffer

A

acetic acid, citric acid, glycine, phosphoric acid

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5
Q

preservatives

A

alcohols, acids, esters, quartenary ammonium compounds
chlorobutanol anhydrous
benzalkonium chloride
sodium benzoate

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6
Q

alcohol

A

ethanol, benzyl alcohol, chlorobutanol

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7
Q

acids

A

benzoic acid, sorbic acid

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8
Q

esters

A

parabens

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9
Q

quart ammoniums

A

alkonium, amonium

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10
Q

antioxidants

A

free radical scavengers, reducing agents, chelating agents

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11
Q

free radical scavengers

A

esters of gallic acid, BHA, BHT, tocopherols, vitamin E
(delayed oxidation)

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12
Q

reducing agents

A

sodium bisulfite, ascorbic acid, thiols (preferential oxidation)

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13
Q

chelating agents

A

citric acid, EDTA
(antioxidant synergists)

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14
Q

emulsifying agents

A

surfactants, hydrophilic colloids (polymers), finely divided solid particles

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15
Q

surfactants

A

anionic, cationic, zwitterionic, nonionic, sulfonate, idium chloride, oxide

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16
Q

hydrophilic colloids (polymers)

A

acacia, tragacanth, gelatin

17
Q

finely divided solid particles

A

bentonite, mag al silicate, al hydroxide, charcoal

18
Q

humectant

A

glycerin, propylene glycol

19
Q

emulsifier, thickening agent

A

cetyl alcohol

20
Q

oil phase

A

liquid petrolatum

21
Q

structured vehicle system

A

polymer: cellulose, xanthan gum, polyvinyloyrrolidone
clay: bentonite, mag al silicate

22
Q

wetting agent/surfactant

A

polysorbate 80 (tween 80)

23
Q

potassium sorbate

A

buffering agent, preservative