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Dosage Forms 2 > Dosage Exam 1 > Flashcards

Dosage Exam 1 Flashcards

0
Q

EDTA

A

Cheating agent

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1
Q

Sodium bisphosphate

A

Antioxidant reducing agent

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2
Q

Butylated hydroxytoluene

A

Antioxidant free radical stabilizer

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3
Q

Sorbitol solution

A

Sweetener

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4
Q

Glycerin

A

Cosolvent

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5
Q

Methyl paraben

A

Preservative acting by lipophilic adsorption

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6
Q

Benzalkonium chloride

A

Preservative acting by electrostatic adsorption

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7
Q

Ascorbic acid

A

Antioxidant and buffer

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8
Q

Chlorpromazine

A

Active ingredient

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9
Q

Citric acid

A

Antioxidant and chelating agent

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10
Q

EDTA

A

Chelating agent and antioxidant

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11
Q

Propylene glycol

A

Co solvent

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12
Q

Sodium bisulfite

A

Antioxidant

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13
Q

Sodium do hydrogen citrate

A

Buffer and cheating agent

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14
Q

Sucrose

A

Sweetener

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15
Q

Water

A

Solvent, water phase, aqueous phase

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16
Q

Benzoyl alcohol

A

Preservative

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17
Q

Cetyl alcohol

A

Emulsifier and thickener

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18
Q

Glycerin

A

Humectant(holds moisture)

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19
Q

Liquid petrolatum

A

Oil phase

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20
Q

Magnesium aluminum silicate

A

Emulsifier, flocculating agent, structured vehicle system

21
Q

Capsicum

A

Active ingredient

22
Q

Menthol

A

Active ingredient

23
Q

Mineral oil

24
Q

Polysorbate 60

A

Emulsifier

25
Q

Propylene glycol

26
Q

Sodium lauryl sulfate

A

Emulsifier

27
Q

Stearyl alcohol

A

Emulsifier, thicken oil phase

28
Q

What is the difference between dispersion and flocculation?

A

Floculants settle fast but less prone to compaction and break up easily.
Dispersion settles as a cake, irreversible, difficult to break up.

29
Q

Newtonian flow

A

Water flows in proportion to force. Linear slope.

30
Q

Plastic

A

Liquid does not flow proportional to force initially then catches up ( ketchup) shear thinning

31
Q

Pseudoplastic

A

Takes more force than plastic to flow, eventually catches up

32
Q

Dilatant

A

High solids content. Becomes thicker with stress shear thickening

33
Q

3 types of non Newtonian flow

A

Plastic
Pseudo plastic
Dilatant

34
Q

Thixotropy

A

Ability of a system that was disturbed by shear stress to return to it’s undisturbed structure. Keeps particles from sinking too quickly but need plastic or pseudo plastic properties for good flow.

35
Q

Wetting

A

A surface active agent added to reduce the surface tension Water enters the pore and displaces the air. Same as surfactant in emulsions.

36
Q

What are the 3 steps in order to prepare a suspension?

A

Reduce particle size
Wetting
Addition of dispersion medium and uniformity is established.

37
Q

Budosenide

A

Active ingredient

38
Q

Magnesium aluminum silicate

A

Structured vehicle system

39
Q

Carboxymethycellulose sodium

A

Structured vehicle system

40
Q

Ploysorbate 80

A

Wetting agent

41
Q

Disodium EDTA

A

Chelating agent

42
Q

Potassium sorbate

A

Preservative and buffer ( ionized not a buffer, has an unionized partner, sorbic acid)

43
Q

Attapulgite

A

Active ingredient

44
Q

Benzoin acid

A

Preservative

45
Q

Citric acid

A

Buffer and chelating agent

46
Q

Magnesium aluminum sylicate

A

Structured vehicle system

47
Q

Methyl paraben and propyl paraben

A

Preservatives

48
Q

Sodium dihydrogen citrates

49
Q

Sorbitol

50
Q

Xanthan

A

Structured vehicle system

51
Q

Methylcellulose

A

Structured vehicle system.

Dosage Forms 2 (2 decks)

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