Dopamine Hydrochloride Flashcards
Names
Dopamine Hydrochloride (Inotropin)
Class
Vasopressor: sympathomimetic (both alpha and beta properties)
Action
- At low and medium doses, selectively dilates blood vessels supplying the brain, kidneys, heart and gastrointestinal tract
- At medium to high doses, increases cardiac output by improving contratility and stroke volume, thereby increasing blood pressure
- At high doses, causes vasoconstriction and increased heart rate
Onset / Duration
ONSET = < 5 minutes DURATION = approximately 10 minutes after the drip is stopped
Indications / Dosage: Discomfort / Pain Suspected Cardiac Origin (S-126)
With associated shock if BP is refractory to second fluid bolus
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Indications / Dosage: Shock Suspected Cardiac (S-138)
If BP is refractory to second fluid bolus
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Indications / Dosage: Shock Suspected Anaphylactic, ? Neurogenic (S-138)
If BP refractory to fluid boluses
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Indications / Dosage: Sepsis (S-143)
If BP refractory to fluid boluses
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Indications / Dosage: Anaphylaxis (S-122)
Shock refractory to fluid boluses and Epinephrine IV/IO
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Indications / Dosage: Dysrhythmias (S-127)
Bradycardia: after max atropine or initiation of TCP
ADULTS ONLY:
10-40mcg/kg/min IV/IO drip infusion:
Titrate to maintain systolic BP ≥ 90 not to exceed 120 BHO
Contraindications
None
Side Effects
- At high infusion rates, hypertension and extreme vasoconstriction may occur
- At low infusion rates, hypotension may occur
- Tachyarrhythmias / palpations
- Increased myocardial O2 demand
Special Information: Packaging
400mg in 250ml NS = 1,600mcg / 1 ml
Special Information: Administration
- Always confirm calculations and dose according to the dopamine drip chart
- Titrate dosing to maintain systolic BP ≥ 90 not to exceed 120
- Always run as piggyback drip, never run as primary IV. Turn primary line off during Dopamine infusion.
Special Information: Cautions & Considerations
• Tissue necrosis occurs with infiltration; check IV patency before and during administration watching for signs of infiltration; if this occurs, discontinue the IV, circle infiltrated area and inform receiving hospital.
