Dopamine Flashcards

1
Q

Dopamine category

A

Amine

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2
Q

Dopamine synthesis area

A
  1. Substantia nigra (pars compacta)
  2. VTA
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3
Q

Dopamine projection areas

A
  1. Nigro-striatal: striatum
  2. Meso-cortical/limbic: NAc and PFC
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4
Q

Dopamine functions

A

Nigro-striatal: modulates cortical motor control and action selection

Meso-cortical/limbic: reward processing, motivation, modulation of cognitive control

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5
Q

Dopamine receptors

A
  1. D1: excitatory
  2. D2: inhibitory
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6
Q

Dopamine disorders

A

Parkinsons: failure of nigro-striatal loop, substantia nigra neurons degeneration

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