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Y4 PSYCH drugs - antipsychotics + anti-dementia drugs > Donepezil > Flashcards

Donepezil Flashcards

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1
Q

What class of drug is donepezil?

A

-Reversible cholinesterase inhibitor
-Inhibit acetylcholinesterase leading to increased availability of acetylcholine
-High specificity which may reduce side effects

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2
Q

What side effects does donepezil have?

A

-Dose-related GISEs (diarrhoea, N+V)
-Agitation, aggression
-Ulcers, cardiac conduction blocks, TIAs (rare)

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3
Q

What is the recommended dose of donepezil?

A

-5-10mg given at bedtime

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Y4 PSYCH drugs - antipsychotics + anti-dementia drugs (13 decks)

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