DOC Flashcards
Latent Mtb
Rif or INH (monotherapy)
Active Mtb
Rifampin
INH
Pyrizidamide
Ethambutol
(Streptomycin and rifabutin is an option)
Substitute for TB in HIV infected individuals
Rifabutin instead of Rifampin
Drug resistant TB
streptomycin
MAC
- Clarithro/Azithro
- Ethambutol
- Tetracycline, doxycycline, ciprofloxacin (prego)
x12 monts
(IV Amikacin if resistant)
Mycobacterium Leprae
Rifampin + Dapsone (treat longer for MB)
Malaria
chloroquine > atovoguine/proguanil = lumefantrine > quinine (complicated) > mefloquine > pyrimethamine/sulfadoxine
Malaria cure for tissue infection
Primaquine + blood schizonticide
DOC for intermittent malaria tx in pregnant women
pyrimthamine/sufadoxine
Herpes
Acyclovir/valacyclovir
OTC herpes treatment
doconosol
CMV
Ganciclovir
Resistant HSV and CMV infections
Foscarnet or cidofovir
Influenza
Oseltamivir
Zanamivir (inhaler)
RSV
Ribavirin
Hep B
Tenofivir
Alternate Hep B drugs
Entecavir
Lamivudine
Cure for HCV
Harvoni
Tx for HCV 1
Harvoni, eplusa
Tx for HSV 4
Zepatier
E. hysitolytica, G. lamblia, T. vaginalis
Metronidazole > Tinidazole > Emetine/dehydroemetine
Asymptomatic amebiasis
Iodoquinol, paramomycin, tetracycline, erythromycin
Toxoplasmosis
Daraprim (pyrimethamine sulfadiazine)
PCP
Bactrim > Pentamidine
Systemic fungal infection
Ampho B
CNS fungal infection
Flucytosine + ampho B
Cryptococcus
flucytosine + ampho B
Ketoconazole
not DOC; shampoo, cream only
Fluconazole
suppressive tx in HIV +
Aspergillus
Vorinconazole > itraconazole > azoles for resistant (caspofungin, micafungin, anidulafungin)
Onychomycosis
Griseofulvin > Terbinafine
Candida
Nystatin