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Junior - Pharm II - 3 > DOC > Flashcards

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1
Q

Syphilis (T. Pallidum)

A

Penicillin G Bicillin La

Natural penicillins - 1st gen

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2
Q

PCN sensitive gangrene (c. Perfringen)

A

Natural PCN - 1st gen

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3
Q

Animal bites

A

Amoxicillin/clavulanate (augmentin)

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4
Q

Human bites

A

Early: amoxicillin/clauvalante PO x 5 days

Later: Ampicillin/Sulbactam IV Q6H or Cefoxitin 2 grams IV q 8h.

PCN allergic​: Clindamycin + either Ciprofloxacin or TMP/SMX

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5
Q

n. Gonorrhea “coming out of their wherever”

A

Ceftriaxone (rocephin) IV

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6
Q

Meningitis

A

3rd gen cephalosporin

Ceftriaxone

Not for neonate: ca2+ crystals in lungs and biliary slugging

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7
Q

Pre/post surg not in abdomen

A

Cefazolin (ancef)

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8
Q

Mild or moderate C. Difficile

A

Metronidazole x 10-14 days

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9
Q

Severe C. Difficile

A

Vancomycin PO x 10-14 days

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10
Q

Mild to moderate CAP

A

Macrolides: clarith or azithro

Doxy

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11
Q

E. Coli, klebsiella, P. Areuginosa, acinobacter (gram -)

A

Aminoglycosides

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12
Q

Anthrax (inhalation, cutaneous and GI)

A

Ciprofloxacin

Or

Doxycycline

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13
Q

Impetigo

A

Mupirocin (bactroban)

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14
Q

Tularemia (francisella tularensis)

A

Streptomycin IV or gentamicin

Alt doxy/ciprofloxacin

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15
Q

Brucellosis

A

Doxycycline

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16
Q

Q-fever (coxiella burnetii)

A

Doxycycline

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17
Q

Uncomplicated cystitis

A 
TMP/SMX x 3 days
Or
Nitrofuratonin x 5 days 
Or
Fosfomycin x 1 dose
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18
Q

Uncomplicated pyelonephritis

A

TMP/SMX x 14 days
Or
Fluroquinolone x 5-7 days

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19
Q

Complicated UTI

A

Fluoroquinolone (2nd, 3rd, or 4th gen)

Aminoglycosides

Extended spectrum b-lactam

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20
Q

UTI in pregnancy

A 
7 days of: 
Amoxicillin
Or 
Nitrofurantoin 
Or
Cephalexin
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21
Q

Never use in pregnancy

A

Fluroquinolones
TMP/SMX
Aminoglycosides
Tetracyclines

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22
Q

CAP w no comorbitdities

A

Macrolides:

  • clarithromycin
  • azithromycin

Or doxycycline

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23
Q

CAP w comorbidities or abx in last 3 months

A

Resp fluoroquinolone

  • moxifloxacin
  • levofloxacin

Macrolide or doxy plus:

  • amoxicillin
  • amoxicillin/cauvulanate
  • ceftriaxone (IV/IM)
  • cefpodoxime
  • cefuroxime
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24
Q

Inpatient CAP

A

Anti-pneumococcal B-lactam + azithromycin

Anti-pneumococcal B-lactam + moxifloxacin or levofloxacin

PCN allergy: aztreonam + moxifloxicin or levofloxacin

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25
Q

Pneumona w P. Aeruginosa

A 
Antipseudomonal B-lactam 
\+
Ciprofloxacin or levofloxacin
Or 
aminoglycoside + azithromycin
Or
Aminoglycoside + ciprofloxacin or levofloxacin
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26
Q

Hospital/ventilator acquired pneumonia

A

MRSA coverage: vancomycin or linezolid

P. aeruginosa: 
Antipseudomonal B-lactam 
\+
Ciprofloxacin or levofloxacin
Or 
aminoglycoside + azithromycin
Or
Aminoglycoside + ciprofloxacin or levofloxacin
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27
Q

MRSA

A
  • Trimethoprim/sulfamethoxazole (PO/IV)
  • Clindamycin (PO/IV)
  • Doxycycline (PO/IV)
  • Vancomycin, dalbavancin, oritavancin, or telavancin (IV)
  • ceftaroline (IV)
  • linezolid or tedizolid (PO/IV)
  • daptomycin(IV)
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28
Q

Relapse or resistant C. Difficile

A

Intracolonic vancomycin

Fidaxomicin x 10 days

Fecal microbiota transplant

Subtotal colectomy

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29
Q

Anti-fungal

A

You made it 2 sections

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30
Q

Fungal pneumonia that doesnt respond to antifungals

A

Sulfamethozazole/trimethoprim (septra)

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31
Q

Vaginal candidiasis

A

Fluconazole

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32
Q

Candida prophylaxid in hematopoietic cell transplant recipients

A

Micafungin (mycamine)

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33
Q

Invasive candidiasis including candidemia

A

Caspofungin (cancidas)

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34
Q

Oral tx of onychomycosis

A

Terbinafine or itraconazole

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35
Q

Tinea versicolor

A

Ketaconazole 2% cream x 2 weeks

36
Q

Fungal infections including invasive and noninvasive candidiasis and cryptococcal disease

A

Fluconazole (diflucan)

37
Q

Prophylaxis against invasive fungal infections in AIDs

A

Fluconazole (diflucan)

38
Q

Invasive pulmonary or extra pulmonary infections caused by candida spp

A

Voriconazole (Vfend)

39
Q

Prophylaxis against asperigullosis and candida infections in AIDS

A

Posaconazole

40
Q

Aspergillus infections

A

Voriconazole (Vfend)

41
Q

Oncychomycosis

A

Terbinafine (lamisil) or itraconazole PO

Toenails x 12 wk
Fingernails x 6 wk

42
Q

Serious invasive fungal infection

A

Amphotericin B

43
Q

Candida infections in AIDS

A

Fluconazole

Posaconazole

44
Q

Uncomplicated vulvovaginal candidiasis (VVC)

A

Flucanazole

45
Q

Antimycobacteral

A

You made it another lecture

46
Q

Active TB in pregnant

A

INH
Rifampin
Ethambutol

X 9 months

No streptomycin

47
Q

LTBI in kids 2-11 and comorbid adults (preggo/AIDS)

A

INH + pyridoxine(B6)

X 9 months

48
Q

LTBI over 12

A

INH and rifampin x 3 months

49
Q

Mycobacterium avium complex (MAC)

50
Q

TB infection

51
Q

Latent TB

52
Q

Combination for:
M. TB
M. LEprae
M. Kansasii

53
Q

Prophylactically or tx of

Meningitis caused meningococci or H. influenzae

54
Q

LTBI tx for preggo

A

INH 1 x daily x 9 months

Pyridoxine supplements

55
Q

Multi drug therapy for M. TB

A

INH: isoniazid
RIF: rifampin
PZA: pyrazinamide
EMB: ethambutol

56
Q

Second line for TB

A

Rifabutin
Rifapentine
Streptomycin

57
Q

Active TB in preggo

A

INH, RIF, EMP x 9 months

58
Q

M. Leprae aka hansen’s disease

A

Less severe:
-dapsone + rifampin x 6-12 mo

More severe:
Dapsone + rifampin + cofazimine x 12-24 mo

59
Q

Viral lecture

A

You survived TB

60
Q

Cytomegalovirus, tx and prevention

A

Ganciclovir (cytovene-IV)

Valganciclovir (prodrug)

61
Q

2nd line for CMV

A

Foscarnet (foscavir) IV

Cidofovir (vistide) IV

62
Q

Prevent CMV post transplant

A

Valganciclovir (valcyte) PO

63
Q

Influenza in preggo

A

Oseltamivir

64
Q

HBV

A

Pegasys

  • a= preferred for HBV
  • b= FDA approved for HBV
65
Q

HBeAG pos

A

1st line: (4-12 mo)

  • INFa
  • PEG-INFa
2nd line (>12 mo)
- entecavir or tenofovir PO
66
Q

HBeAG neg

A

1st line (at least 12 mo)

  • INFa
  • PEG-INFa
2nd line (>12 mo)
- entecavir or tenofovir PO
67
Q

Oral agents for HBeAg pos and HBeAG neg?

A

Entecavir and tenofovir

68
Q

Resistant HBV

A

Lamivudine or telbivudine resistance:

  • add adefovir or tenofovir or
  • change to entecavir

Adefovir resistance:
- add lamivudine

Entecavir resistance:
- change to tenofovir

69
Q

Shingles (herpes zoster)

A

Vanacyclovir
Famciclovir
Acyclovir

70
Q

Genital herpes simplex

A

Vanciclovir

71
Q

HIV+ preggo

Antepartum stage

A

Emtricitabine/tenofovir (truvada)

Raltegravir (isentress)

72
Q

HIV + preggo

Intrapartum

A

Antepartum +

Zidovudine

73
Q

HIV+ mom

Infant prophylaxis

A

Low risk: zidovudine 4-6 weeks

High risk: combo regimen

74
Q

Occupational (<72hrs) post exposure prohyplaxis (PEP)

A

Emtricitabine/tenofovir (truvada)

Raltegravir (isentress)

75
Q

Herpes encephalitis

A

Acyclovir IV q 8 hrs’
Followed by
Oral antiviral q 10 days

76
Q

Difficult to treat HSV infection

A

Acyclovir IV

77
Q

HIV pre-exposure prophylaxis (PrEP)

A

Emtricitabine (FTC)
+
Tenofovir disoproxil fumarate (TDF) (truvada)

78
Q

Treatment experienced pts that blocks HIV fusion w CD4 pt to block entry into human cell?

A

Enfuviritide (fusion inhibitor)

79
Q

Parasite

A

Thank god, another one down

80
Q

Hydrocele from lymphatic filariasis (roundworm, elephantiasis)

81
Q

Lymphatic filariasis

A

Diethycarbamazine (DEC)

82
Q

Sensitive p. falciparum

A

Chloroquine (aralen)

83
Q

Chemoprophylaxis in areas w chloroquine resistant P. Falciparum

A

Doxycycine (vibramycine)

84
Q

Mild to moderate C. Diff

A

Metronidazole

85
Q

Trichomas vaginalis

A

Metronidazole or tindazole

86
Q

Pneumpcystis jiroveci pneumonia (PCP)

A

Sulfamethozazole/trimethoprim (septra)

Junior - Pharm II - 3 (1 decks)

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